Pittsburgh Pirates vs Cincinnati Reds MLB Betting Prediction

MLB Pittsburgh Pirates vs Cincinnati Reds Prediction 9/24

The Pittsburgh Pirates will visit the Cincinnati Reds on Wednesday, September 24, 2025. The game will be held at Great American Ball Park in Cincinnati, OH, and is set to start at 6:40 PM. The Pirates come in with a record of 68-89, while the Reds hold a record of 80-77. Weather conditions are expected to include light rain with calm winds. Fans can catch the game on SN PT.

Pirates vs. Reds Betting Prediction

  • Money Line Prediction: Pittsburgh Pirates -101. The Pirates have won their last three games, including a recent victory over the Reds. Their current form makes them a good pick at this moneyline.
  • Over/Under Prediction: Under 7.0 (-116). Both starting pitchers have low ERAs, and recent games between these teams have been low-scoring.

Team Trends

  • The Pittsburgh Pirates have a road record of 24-52 this season.
  • The Cincinnati Reds hold a home record of 44-35 this season.
  • The Pirates are on a 3-game winning streak, with their latest win against the Reds, 4-2.
  • The Reds have won 6 of their last 10 games.
  • The game will be played at Great American Ball Park, where the weather forecast predicts light rain.

Pirates vs Reds Preview

The Pittsburgh Pirates are set to play the Cincinnati Reds on Wednesday evening. With a record of 68-89, the Pirates are looking to extend their current winning streak to four games. They will rely on their pitcher, Paul Skenes, who has an ERA of 2.03 and a WHIP of 0.96. Skenes has a balanced win-loss record of 10-10 this season.

The Cincinnati Reds, holding a record of 80-77, aim to bounce back from a recent loss. Hunter Greene will take the mound for the Reds, bringing an ERA of 2.74 and a WHIP of 0.93. Greene has secured seven wins and four losses this season. Both teams will have to contend with light rain and calm winds at Great American Ball Park.

Reds’ Key Players and Stats

The Cincinnati Reds have some strong hitters this season. Elly De La Cruz stands out with a .266 batting average. He leads the team in home runs with 21 and has scored 101 runs. Spencer Steer is another important player for the Reds. He has a batting average of .240 and has played in 141 games. Steer also has 21 home runs, tying with De La Cruz for the team lead. Matt McLain and Ke’Bryan Hayes add depth to the lineup. McLain has 15 home runs, while Hayes has played in 147 games. Noelvi Marte, in fewer games, has a .269 batting average and 13 home runs.

Pirates’ Lineup Overview

Andrew McCutchen leads the Pittsburgh Pirates with 13 home runs this season. He has played in 131 games and has a .240 batting average. McCutchen also has 57 RBIs, making him a key player for the team. Spencer Horwitz has contributed with a .257 batting average over 103 games. He has hit 9 home runs and scored 50 runs. Horwitz’s on-base percentage is .338, which helps the team get more scoring chances. Jared Triolo and Nick Gonzales add depth to the Pirates’ lineup. Triolo has played in 103 games with a .233 batting average and 7 home runs. Gonzales, in 91 games, has a .264 batting average and 5 home runs.

Final Betting Pick

The Pittsburgh Pirates are on a three-game winning streak, which includes a win over the Cincinnati Reds. This recent form makes them a strong choice for the moneyline at -101. On the road, the Pirates have struggled, but their current momentum could help them continue their winning ways.

The over/under set at 7.0 seems reasonable given the starting pitchers’ performances. Paul Skenes of the Pirates has an ERA of 2.03, while Hunter Greene of the Reds has an ERA of 2.74. Both teams have shown low-scoring tendencies in recent games, supporting the prediction for the game to go under 7.0.


All odds are courtesy of Action247 Sportsbook. Good luck!!


* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.