The San Diego Padres will play against the Chicago White Sox on Saturday, September 20, 2025, at 7:10 PM. The game will take place at Rate Field in Chicago, IL. The weather forecast predicts a warm day with a light breeze and light rain. The Padres have a record of 83-71 and are ranked 2nd in their division, while the White Sox hold a record of 58-96, placing them 5th in their division.

Padres vs. White Sox Betting Prediction

• Money Line Prediction: San Diego Padres -169. The Padres have a better record and are ranked higher in their division. Despite a recent losing streak, their overall performance this season makes them the better choice against the White Sox.
• Over/Under Prediction: Under 8.5 (-113). Both teams have shown limited scoring ability in recent games, and the weather forecast of light rain might further limit scoring opportunities.

Team Trends

• The San Diego Padres have a road record of 36-43 this season.
• The Chicago White Sox hold a home record of 33-46.
• The Padres recently lost to the White Sox 4-3 on September 19, 2025.
• The White Sox are currently on a one-game winning streak.
• The Padres have lost their last two games.

Padres vs White Sox Preview

The San Diego Padres are set to take on the Chicago White Sox at Rate Field. The Padres aim to break their two-game losing streak. They are currently 2nd in their division with an 83-71 record. The White Sox, with a 58-96 record, are 5th in their division. They recently won their last game and hope to continue that momentum.

Yu Darvish will start for the Padres. He has a 5.63 ERA and a 1.14 WHIP. The White Sox will counter with Yoendrys Gómez. Gómez holds a 4.91 ERA and a 1.42 WHIP. Both pitchers will look to give their teams a strong performance in this night game.

Chicago White Sox: Key Players and Stats

Miguel Vargas plays third base for the Chicago White Sox. He has a batting average of .228 over 131 games. Vargas has hit 15 home runs and leads the team with 73 runs. Lenyn Sosa is the second baseman for the team. He has played in 133 games with a batting average of .261. Sosa has 20 home runs and 70 RBIs, making him a key player. Yoendrys Gómez is set to start as the pitcher for the White Sox. He has an ERA of 4.91 and a WHIP of 1.42. Gómez has a win-loss record of 3-2 this season.

San Diego Padres: Key Players and Season Overview

Manny Machado is a top player for the Padres. He has a batting average of .277 in 153 games. Machado leads the team with 26 home runs and 92 RBIs. Luis Arraez is another important player for the Padres. He has a batting average of .287 over 147 games. Arraez has contributed 57 RBIs and 61 runs this season. Yu Darvish is set to pitch for the Padres. His ERA is 5.63 with a WHIP of 1.14. Darvish has a win-loss record of 4-5 for the season.

Final Betting Pick

The Padres have a stronger record this season with 83 wins compared to the White Sox’s 58 wins. This gives them an edge, even though they are playing away. Their overall road record is not as strong, but they have managed to win key games on the road.

The under 8.5 total seems reasonable given both teams’ recent performances. The Padres have struggled to score more than a few runs in recent games, and the White Sox have also shown limited scoring. With the weather forecast predicting light rain, this could further suppress scoring opportunities, making the under a solid pick.

All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.