The San Francisco Giants and the St. Louis Cardinals will meet on Sunday, September 7, 2025, at 2:15 PM. The game will take place at Busch Stadium in St. Louis, MO. Fans can expect clear skies and a light breeze during this afternoon game, which will be broadcast on FDSMW.
Giants vs. Cardinals Betting Prediction
- Money Line Prediction: San Francisco Giants +125. The Giants have been strong on the road with a 37-36 record, and they have won 8 of their last 10 games. This makes them a good value pick against the Cardinals.
- Over/Under Prediction: Over 8.0 (-103). With Kai-Wei Teng’s high ERA of 7.23 and Sonny Gray’s recent struggles, both teams could score enough to push the total over 8 runs.
Team Trends
- San Francisco Giants have a road record of 37-36 this season.
- St. Louis Cardinals have a home record of 40-34 this season.
- In their last game, St. Louis Cardinals won 3-2 against the San Francisco Giants.
- San Francisco Giants have won 8 of their last 10 games.
- The game will be played at Busch Stadium in St. Louis, MO, with clear skies expected.
Giants vs Cardinals Preview
The San Francisco Giants head to Busch Stadium to take on the St. Louis Cardinals. The Giants hold a record of 72-70 and are ranked third in their division. They have been strong lately, winning eight of their last ten games, although they lost their most recent game.
The Cardinals, with a 71-72 record, sit fourth in their division. They won their last game and have secured six wins in their last ten. Starting on the mound for the Giants is Kai-Wei Teng, who has a 7.23 ERA. Sonny Gray will pitch for the Cardinals, coming in with a 4.43 ERA. Fans can expect a mild day with clear skies for this afternoon game.
Cardinals’ Key Players and Stats

The St. Louis Cardinals have a strong lineup with Willson Contreras leading the team in home runs and RBIs. Contreras has hit 20 home runs and driven in 78 runs, ranking first on the team in both categories. His batting average stands at .254, matching Masyn Winn, who has also been a reliable player.
Alec Burleson is another top performer for the Cardinals, with a batting average of .286. He has hit 16 home runs and has 60 RBIs, ranking second on the team in both. Brendan Donovan contributes with a .279 batting average and leads the team with 57 runs scored.
On the mound, Sonny Gray will start for the Cardinals. Gray has a 12-8 record with a 4.43 ERA and a 1.23 WHIP. His performance will be crucial as the Cardinals aim to improve their 4.29 team ERA, which ranks 21st in the league.
Giants’ Road Challenges
Rafael Devers is a key player for the Giants. He has played 143 games and has a batting average of .263. Devers leads the team with 31 home runs and 99 RBIs. Willy Adames plays shortstop for the Giants. He has a batting average of .229 and has hit 27 home runs. Adames has also scored 86 runs, tying with Devers for the team lead. Kai-Wei Teng will pitch for the Giants. He has a record of 2-3 with an ERA of 7.23. The Giants’ team ERA is 3.78, which ranks 6th in the league.
Final Betting Pick
The San Francisco Giants are a solid pick for the money line at +125. They have a strong road record of 37-36 and have won 8 of their last 10 games. This shows they perform well away from home, making them a good choice against the Cardinals.
For the over/under prediction, the over 8.0 runs is a good bet. Kai-Wei Teng’s ERA of 7.23 suggests he might allow several runs. Sonny Gray has also struggled recently, which could lead to a high-scoring game. Both teams have the potential to score enough to surpass 8 runs.
All odds are courtesy of Action247 Sportsbook. Good luck!!
* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.
Last updated:September 7, 2025 Cardinals, Giants