The St. Louis Cardinals will take on the Milwaukee Brewers on Friday, September 12, 2025, at 8:10 PM. The game will be held at American Family Field in Milwaukee, WI. Both teams are looking to break their three-game losing streaks in this NL Central showdown.

Cardinals vs. Brewers Betting Prediction

• Money Line Prediction: Milwaukee Brewers -185. The Brewers have a strong home record of 46-26 and a better overall season record. Their starting pitcher, Quinn Priester, has a solid ERA of 3.25 and a 12-2 record, which gives them an edge.
• Over/Under Prediction: Under 8.5 (-119). Both teams have been struggling offensively in recent games, and with Priester’s strong pitching, a lower-scoring game is likely.

Team Trends

• The St. Louis Cardinals have a road record of 31-41 this season.
• The Milwaukee Brewers have a strong home record of 46-26.
• Both the Cardinals and Brewers are on a losing streak of three games.
• The Cardinals are 17 games behind in the NL Central Division.
• The Brewers hold the first place in the NL Central Division.

Cardinals vs Brewers Preview

The St. Louis Cardinals are set to challenge the Milwaukee Brewers in an NL Central game. The Cardinals, with a 72-75 record, are in the fourth spot in their division. Andre Pallante will take the mound for the Cardinals. He has a 5.28 ERA and a 6-13 record this season. The Cardinals hope to end their three-game losing streak.

The Milwaukee Brewers hold the top position in the division with an 89-58 record. Quinn Priester is the starting pitcher for the Brewers. He has a solid 3.25 ERA and a 12-2 record. Both teams are eager to break their recent losing streaks in this game at American Family Field.

Brewers Ready for Action

The Milwaukee Brewers have a strong lineup this season. Brice Turang stands out with a .289 batting average. He has played in 141 games, leading the team in home runs, runs, and RBIs. William Contreras also plays an important role for the Brewers. He has a .263 batting average and has appeared in 140 games. His performance ranks him second in home runs, runs, and RBIs for the team. Quinn Priester is the starting pitcher for this game. He holds a 3.25 ERA and a 12-2 win-loss record. The Brewers rank high in both team hitting and pitching, making them a tough team to beat.

Cardinals Seek Strong Performance

The St. Louis Cardinals have some key players in their lineup. Willson Contreras leads the team with 20 home runs and 78 RBIs. His batting average is .253, making him a player to watch. Alec Burleson also contributes with a .282 batting average. He has 17 home runs and 62 RBIs. Masyn Winn adds depth with a .253 average and leads the team in runs. Andre Pallante is the starting pitcher for the Cardinals. He has a 5.28 ERA and a 6-13 win-loss record. The Cardinals’ pitching ranks lower, but Pallante will aim to improve.

Final Betting Pick

The Milwaukee Brewers are a solid pick for the money line at -185. They have a strong home record of 46-26, which indicates they perform well at American Family Field. Their starting pitcher, Quinn Priester, has an impressive ERA of 3.25 and a 12-2 record, giving them an advantage on the mound. The Brewers’ overall season record of 89-58 also shows they are a strong team this year.

For the over/under prediction, going under 8.5 seems reasonable. Both teams have struggled offensively in recent games. The Cardinals have not scored more than five runs in their last five games. With Priester’s strong pitching and the Brewers’ ability to limit opponents, a lower-scoring game is likely.

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All odds are courtesy of Action247 Sportsbook. Good luck!!

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* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.