St. Louis Cardinals vs Pittsburgh Pirates MLB Betting Prediction

MLB St. Louis Cardinals vs Pittsburgh Pirates Prediction 4/7

On Monday, April 07, 2025, the St. Louis Cardinals will play against the Pittsburgh Pirates at PNC Park. The game is set to begin at 6:40 PM and will take place under the night sky. Fans can look forward to seeing these teams compete on the Pirates’ home field.

Cardinals vs. Pirates Betting Prediction

  • Money Line Prediction: Cardinals MoneyLine: -123. The Cardinals have a better overall record and a strong home performance. Their batting stats are also superior, making them a solid pick.
  • Over/Under Prediction: Under 8.5 (-115). Both teams have struggled with pitching, but the Pirates’ low batting average suggests fewer runs, keeping the total under.

Team Trends

  • The St. Louis Cardinals have a home record of 4-2 this season.
  • The Pittsburgh Pirates are 3 games back in the NL Central.
  • In a recent game against the Boston Red Sox, the Cardinals had 12 hits but still lost 18-7.
  • Andrew Heaney of the Pirates struck out 10 batters in a win against the Yankees.
  • Iván Herrera hit 3 home runs in a Cardinals win over the Los Angeles Angels.

Cardinals vs Pirates Preview

The St. Louis Cardinals will meet the Pittsburgh Pirates at PNC Park on Monday night. The game starts at 6:40 PM, and both teams are ready to play under the lights. Matthew Liberatore will pitch for the Cardinals. In his last game, he pitched six innings against the Angels, allowing three runs.

Carmen Mlodzinski will pitch for the Pirates. His last regular season appearance was not great, with an ERA of 9.82. During spring training, he had better results with an ERA of 3.72. Both teams will rely on their pitchers to set the tone for the game.

Pirates’ 2025 Season Overview

The Pittsburgh Pirates have had a mixed start to their 2025 season. Their batting average stands at .197, placing them 23rd in the league. However, they lead the league in stolen bases with 21, showing their speed on the bases. Oneil Cruz has played in 10 games and has a batting average of .242. He has hit 2 home runs and driven in 4 runs. Ke’Bryan Hayes has a slightly better average of .257 with 1 home run and 4 RBIs. Carmen Mlodzinski has pitched 3 2/3 innings this season with an ERA of 9.82. The Pirates’ team ERA is 4.98, ranking them 25th. They have allowed 6 home runs, which is the third fewest in the league.

Cardinals’ Strengths and Challenges

The St. Louis Cardinals have shown strong batting skills early in the season. Their team batting average is .301, the best in the league. Lars Nootbaar is a key player with a .333 average, 2 home runs, and 10 runs scored. Iván Herrera has been impressive with a .381 average and 4 home runs. However, he is currently out due to knee inflammation. This absence might affect the team’s performance behind the plate. Matthew Liberatore will pitch for the Cardinals. He has an ERA of 4.50 from his first game of the season. In spring training, his ERA was 1.62 over 16 2/3 innings.

Final Betting Pick

The Cardinals are favored on the money line at -123. They have a strong home record of 4-2, which gives them an edge. Their batting average is .301, ranking first, and they lead in on-base percentage as well. These stats suggest they have a better chance of winning against the Pirates, who have a lower batting average of .197.

The over/under is set at 8.5, and the prediction is for the total to stay under. The Pirates have struggled with a low slugging percentage of .296, which is 28th in the league. The Cardinals’ pitching has a high ERA of 6.01, but the Pirates’ offense might not capitalize due to their hitting struggles. This could lead to fewer runs in the game.


All odds are courtesy of Action247 Sportsbook. Good luck!!


* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.