St. Louis Cardinals vs Seattle Mariners MLB Betting Prediction

MLB St. Louis Cardinals vs Seattle Mariners Prediction 9/10

The St. Louis Cardinals will play against the Seattle Mariners on Wednesday, September 10, 2025, at T-Mobile Park in Seattle, WA. The game starts at 9:40 PM and will be broadcast on FDSMW. The Cardinals have a record of 72-74, while the Mariners are at 77-68. The weather forecast predicts clear skies with a mild breeze, but the retractable roof may prevent any wind impact on the game.

Cardinals vs. Mariners Betting Prediction

  • Money Line Prediction: Seattle Mariners -224. The Mariners have a strong home record of 43-27 and are on a 4-game winning streak. Their recent performance against the Cardinals also shows they have the upper hand.
  • Over/Under Prediction: Under 7.5 (-113). Both teams have shown moderate scoring in recent games, and with Logan Gilbert’s solid pitching stats, a low-scoring game is likely.

Team Trends

  • The St. Louis Cardinals have a road record of 31-40 this season.
  • The Seattle Mariners have won their last four games.
  • Seattle Mariners have a strong home record of 43-27.
  • The Cardinals lost their last two games against the Mariners, with scores of 5-3 and 4-2.
  • The game will be played at T-Mobile Park, which has a retractable roof.

Cardinals vs Mariners Preview

The St. Louis Cardinals and Seattle Mariners meet at T-Mobile Park for an evening game. The Cardinals hold a record of 72-74 and are ranked fourth in their division. They are on a two-game losing streak, trying to find their footing. Michael McGreevy will start for the Cardinals, bringing an ERA of 4.68 and a WHIP of 1.26.

The Mariners, with a 77-68 record, are second in their division and have won their last four games. Logan Gilbert takes the mound for Seattle, aiming to continue his solid performance with an ERA of 3.61 and a WHIP of 1.02. Both teams are looking to improve their standing as the season progresses.

Seattle Mariners: Power at the Plate

The Seattle Mariners have some strong hitters this season. Cal Raleigh leads the team with 53 home runs. He also ranks first on the team in runs and RBIs with 95 and 113, respectively. Eugenio Suárez is another key player for the Mariners. He has hit 45 home runs and is second on the team in both runs and RBIs. His performance keeps the Mariners competitive in the league. Josh Naylor contributes with a .286 batting average, which is the highest on the team. He also has 19 home runs and 80 RBIs. These stats make him a valuable player for the Mariners.

St. Louis Cardinals: Key Players and Stats

The St. Louis Cardinals have some solid hitters this season. Willson Contreras leads the team with 20 home runs. He also has 78 RBIs, ranking first on the team. His batting average is .256. Alec Burleson contributes with a .285 batting average. He has hit 17 home runs and has 62 RBIs. Burleson is a key player in the Cardinals’ lineup. Masyn Winn adds depth to the team with his performance. He has a batting average of .253 and has scored 72 runs. Winn also has 51 RBIs, making him a reliable player for the Cardinals.

Final Betting Pick

The Mariners are a good pick for the money line at -224. They have a strong home record of 43-27 and are on a 4-game winning streak. Logan Gilbert’s pitching, with an ERA of 3.61, adds to their advantage. The Cardinals have struggled on the road with a 31-40 record, making the Mariners a safer bet.

For the over/under, under 7.5 is a solid choice. Both teams have shown moderate scoring in recent games. The Mariners’ recent games against the Cardinals ended with scores of 5-3 and 4-2. Logan Gilbert’s pitching further supports a low-scoring game, as he has a WHIP of 1.02, which indicates good control on the mound.


All odds are courtesy of Action247 Sportsbook. Good luck!!


* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.