The Chicago White Sox will take on the Washington Nationals on Saturday, September 27, 2025, at 4:05 PM. The game will be held at Nationals Park in Washington, DC. Fans can expect an overcast day as they tune in on CHSN. The White Sox have a record of 59-101, while the Nationals stand at 65-95.

White Sox vs. Nationals Betting Prediction

• Money Line Prediction: Chicago White Sox +101. The White Sox won their last game against the Nationals, and their starting pitcher, Sean Burke, has a better ERA than the Nationals’ Jake Irvin. This gives the White Sox an edge.
• Over/Under Prediction: Over 8.5 (-110). Both teams scored a total of 19 runs in their last game, indicating strong offensive performances. With both starting pitchers having ERAs over 4.00, another high-scoring game is possible.

Team Trends

• The Chicago White Sox have a road record of 26-53 this season.
• The Washington Nationals have a home record of 31-48 this season.
• In their last game, the White Sox won 10-9 against the Nationals.
• Lenyn Sosa from the White Sox had a strong performance in the last game with 3 hits and 3 RBIs.
• The game will be played at Nationals Park, with overcast clouds expected.

White Sox vs Nationals Preview

The Chicago White Sox are set to play against the Washington Nationals at Nationals Park. The White Sox have had a tough season, sitting at the bottom of their division with a 59-101 record. They hope to build on their recent win as they face the Nationals, who hold a 65-95 record and are also ranked fifth in their division.

On the mound, the White Sox will start Sean Burke, who has a 4.29 ERA and a 1.47 WHIP. The Nationals will counter with Jake Irvin, who has a 5.69 ERA and a 1.44 WHIP. Both teams are looking to end their seasons on a positive note. Fans can catch the game on CHSN at 4:05 PM under overcast skies.

Nationals Ready for the Challenge

The Washington Nationals are gearing up for their next game. CJ Abrams leads the team in runs with 92, ranking 18th in the league. His batting average stands at .260, which is solid among his teammates. Luis García Jr. has been a key player for the Nationals. He has 66 RBIs, making him the top RBI contributor on the team. García Jr. has played in 137 games, showing consistency throughout the season. Jake Irvin will be on the mound as the starting pitcher. His record this season is 9 wins and 13 losses, with an ERA of 5.69. The Nationals will look to improve their pitching, as they currently rank 29th in team ERA at 5.33.

White Sox Set to Compete

The Chicago White Sox are preparing for their next game with a focus on their top hitters. Lenyn Sosa is leading the team with 22 home runs, ranking 21st in the league. He has also contributed 75 RBIs, making him the team’s top RBI producer. Miguel Vargas has played in 137 games, showing his durability. He leads the team with 78 runs, ranking 32nd in the league. His batting average is .233, and he has hit 15 home runs this season. On the pitching side, Sean Burke will start for the White Sox. Burke has a record of 4 wins and 11 losses with an ERA of 4.29. The White Sox pitching staff has a team ERA of 4.30, ranking 21st in the league.

Final Betting Pick

The Chicago White Sox have a good chance with Sean Burke as their starting pitcher. Burke’s ERA of 4.29 is better than Jake Irvin’s 5.69. This could help the White Sox, especially since they are coming off a win against the Nationals.

Scoring might be high again, as both teams scored 19 runs in their last game. With both pitchers having ERAs over 4.00, runs could come easily. The White Sox have shown they can score on the road, making the Over 8.5 a solid choice.

All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.