In Week 6 of the 2025 regular season, the Iowa State Cyclones will play against the Cincinnati Bearcats. The game is set for Saturday, October 4, 2025, at Nippert Stadium in Cincinnati, OH. Kickoff is at 12:00 PM and will be broadcast on ESPN2.

Iowa State vs. Cincinnati Betting Prediction

• Money Line Prediction: Iowa State Cyclones +101. Iowa State is ranked higher and has a strong record of 5-0 this season. They have also been successful as underdogs in recent games.
• Over/Under Prediction: Over 54.5. Both teams have been scoring well, with Cincinnati scoring 37 points in their last game and Iowa State scoring 39. This suggests a high-scoring game.

Team Trends

• Iowa State Cyclones are ranked #14 in the AP Poll and #12 in the Coaches Poll.
• Iowa State Cyclones have a perfect 5-0 record this season, with a 1-0 record on the road.
• Cincinnati Bearcats have a 3-1 record this season, with a 2-1 record at home.
• Iowa State Cyclones scored 158 points this season, ranking 26th in points for.
• Cincinnati Bearcats won their last home game against Northwestern State Demons 70-0.

Iowa State vs Cincinnati Preview

The Iowa State Cyclones are off to a strong start this season. They hold a perfect 5-0 record and are ranked 14th in the AP Poll. Their impressive performance includes a 2-0 record in conference games. The Cyclones have shown consistency on both home and road fields, with a recent win in the Pop-Tarts Bowl against Miami. They aim to continue their winning streak against the Cincinnati Bearcats.

The Cincinnati Bearcats have also had a successful start to the season. They have a 3-1 record, with a 1-0 mark in conference play. The Bearcats have been solid at home, winning two out of three games. They are on a three-game win streak and will look to use their home-field advantage at Nippert Stadium to challenge the Cyclones. Both teams are part of the Big 12 conference, adding extra significance to this game.

Cincinnati Bearcats: Key Players and Season Overview

The Cincinnati Bearcats are part of the Big 12 conference. They play their home games at GEHA Field at Arrowhead Stadium. This season, they have a record of 3-1, with a home record of 2-1.

Brendan Sorsby leads the team’s quarterbacks with 1,043 passing yards and 10 touchdowns over four games. Tawee Walker is the top running back with 224 rushing yards and three touchdowns in four games. Cyrus Allen stands out among receivers with 23 receptions, 273 yards, and five touchdowns.

On offense, Cincinnati has scored 158 points and gained 1,152 passing yards and 768 rushing yards. Their defense has given up 74 points while recording 10 sacks and two fumbles recovered. The Bearcats come off a close 37-34 win over Kansas, showing their ability to perform under pressure.

Iowa State Cyclones: A Strong Start to the Season

Iowa State Cyclones are ranked #14 in the AP poll and #12 in the Coaches Poll. They are part of the Big 12 conference and play their home games at Jack Trice Stadium. With a 5-0 record this season, including a 1-0 road record, they are off to an impressive start.

Rocco Becht leads the Cyclones’ quarterbacks with 1,103 passing yards and 7 touchdowns over five games. Carson Hansen is the top running back, rushing for 315 yards and scoring 2 touchdowns. On the receiving end, Brett Eskildsen has contributed 10 receptions for 216 yards and a touchdown in four games.

As a team, Iowa State has scored 158 points with 1,176 passing yards and 760 rushing yards. Their defense has allowed 71 points, along with recording 9 sacks and recovering 2 fumbles. They are coming off a solid 39-14 victory over Arizona, showcasing their strong form this season.

Final Betting Pick

Iowa State has a strong season record of 5-0, making them a solid pick for the money line at +101. They have been successful as underdogs in recent games, winning all three of their last underdog games. Their away record is also strong, with a win in their only road game this season. This shows they can handle the pressure of playing away from home.

The over/under prediction of over 54.5 looks promising. Both teams have shown they can score high points, with Iowa State scoring 39 in their last game and Cincinnati scoring 37. Iowa State’s offense ranks 26th in points for, while Cincinnati’s offense ranks 26th as well. This suggests both teams have the capability to contribute to a high-scoring game.

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All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.