On Saturday, September 27, 2025, the LSU Tigers will visit the Ole Miss Rebels at Vaught-Hemingway Stadium in Oxford, MS. Both teams are undefeated this season with a 4-0 record. The game will start at 3:30 PM ET and air on ABC.

LSU vs. Ole Miss Betting Prediction

• Money Line Prediction: Ole Miss Rebels -119. Ole Miss has a strong home record, winning 27 of their last 30 home games. This makes them a solid choice at home against LSU.
• Over/Under Prediction: Over 54.5. Both teams have shown strong offensive performances this season, with Ole Miss scoring 179 points and LSU scoring 116 points. This suggests a high-scoring game.

Team Trends

• LSU Tigers are ranked #4 in both the AP and Coaches Polls.
• Ole Miss Rebels hold a #13 AP rank and #11 Coaches Poll rank.
• LSU Tigers have a perfect 4-0 record, including a 1-0 road record.
• Ole Miss Rebels are also 4-0, with a 3-0 record at home.
• LSU Tigers scored 56 points against Southeastern Louisiana in their last home game.

LSU vs Ole Miss Preview

The LSU Tigers, ranked #4 in both the AP and Coaches Poll, are ready to take on the Ole Miss Rebels this Saturday. LSU has a strong start with a 4-0 record this season. They have shown strength both at home and on the road, including a recent win at Kinder’s Texas Bowl against Baylor, 44-31. The Tigers are on a 4-game win streak and hold a 1-0 conference record.

The Ole Miss Rebels, ranked #13 in the AP Poll and #11 by the coaches, also hold a 4-0 record. The Rebels have been solid at home with a 3-0 record and a 2-0 mark in conference play. They recently had a commanding win over Duke in the TaxSlayer Gator Bowl, finishing with a score of 52-20. Both teams aim to maintain their unbeaten records in this exciting Southeastern Conference showdown.

Ole Miss Rebels: A Strong Start

The Ole Miss Rebels are ranked #13 in the AP Poll and #11 in the Coaches Poll. They play in the Southeastern Conference and have a perfect 4-0 record this season. The team plays their home games at Vaught-Hemingway Stadium.

Quarterback Trinidad Chambliss has played 4 games and passed for 719 yards. He has 4 passing touchdowns and no interceptions, leading the team in these stats. Another key player, Austin Simmons, has 580 passing yards and also 4 touchdowns.

Running back Kewan Lacy is a top performer with 358 rushing yards and 7 touchdowns in 4 games. In the receiving department, Harrison Wallace III has 343 receiving yards and 2 touchdowns. The Rebels’ offense ranks 10th in points and 9th in passing yards this season.

LSU Tigers: Aiming for Dominance

LSU Tigers are ranked #4 in both the AP and Coaches Polls. They have a 4-0 record this season. Playing in the Southeastern Conference, they have won one conference game.

Quarterback Garrett Nussmeier has thrown for 960 yards in 4 games. He has 6 passing touchdowns and 2 interceptions. Nussmeier leads the team’s passing attack.

Running back Caden Durham has rushed for 213 yards and scored 2 touchdowns. Wide receiver Aaron Anderson has 293 receiving yards. Anderson has caught 21 passes this season.

Final Betting Pick

The Ole Miss Rebels are a strong pick for the money line at -119. They have a great home record, winning 27 of their last 30 games at Vaught-Hemingway Stadium. This gives them an edge against LSU, especially with their current 3-0 home record this season.

The over 54.5 prediction is supported by the offensive strength of both teams. Ole Miss has scored 179 points, and LSU has 116 points this season. With both teams showing high-scoring games, this total seems achievable.

Parlay season is officially here for College Football and NFL season! Action 24/7 is bringing back Parlay Cards, where you can bet small and win big. Choose 5, 10, or 15 games, place your bet, and chase payouts up to $1 Million. Whether you’re watching SEC Saturdays or NFL Sundays, the parlay card is your ticket to high-reward action — only at Action 24/7 online sportsbook.

All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.