The Ole Miss Rebels take on the Kentucky Wildcats in Week 2 of the 2025 regular season. This game is set for Saturday, September 6, 2025, at 3:30 PM. It will be held at Kroger Field in Lexington, KY, and will air on ABC. Both teams enter the game with a 1-0 record this season.

Ole Miss vs. Kentucky Betting Prediction

• Money Line Prediction: Ole Miss Rebels -377. Ole Miss is ranked higher and has a strong offensive record this season. They scored 63 points in their last game, making them a solid choice.
• Over/Under Prediction: Over 52.5. Ole Miss scored 63 points in their last game, and Kentucky’s defense allowed 16 points. This suggests the total could go over.

Team Trends

• Ole Miss Rebels are ranked #21 in the AP Poll and #15 in the Coaches Poll.
• Ole Miss Rebels scored 63 points in their first game of the 2025 season, ranking 9th in the nation.
• Kentucky Wildcats have a 1-0 home record for the 2025 season.
• Kentucky Wildcats’ defense ranks 5th in sacks with 3 in the 2025 season.
• The game will be played at Kroger Field in Lexington, KY, and aired on ABC at 3:30 PM.

Ole Miss vs Kentucky Preview

The Ole Miss Rebels head to Kroger Field to play against the Kentucky Wildcats in Week 2 of the 2025 season. Both teams are coming off wins in their season openers. Ole Miss is ranked 21st in the AP Poll and 15th in the Coaches Poll. They aim to continue their strong start after a big win in the TaxSlayer Gator Bowl last season.

Kentucky also began their season with a win and holds a home record of 1-0. They are not ranked in the AP or Coaches Poll but are looking to improve their standing. The Wildcats have a conference rank of 3rd out of 16 teams. This game will be a test for both teams as they seek to maintain their early momentum.

Kentucky Wildcats Season Opener Success

The Kentucky Wildcats play in the Southeastern Conference and call Kroger Field home. They started the season with a 1-0 record, and they are 1-0 at home. This season, they have not yet played any conference games.

Quarterback Zach Calzada has thrown for 85 yards in one game. Running back Dante Dowdell has 129 rushing yards, ranking him 19th overall. Wide receiver Ja’Mori Maclin has one reception for 11 yards.

The Wildcats’ offense scored 24 points in their first game, ranking 32nd. Their defense allowed 16 points and recorded three sacks, ranking 12th and 5th respectively. Jamarion Wilcox is listed as questionable due to a suspension.

Ole Miss Rebels: A Strong Start

Ole Miss Rebels began their season with a 1-0 record. They have not played any road games yet. Their offense is ranked 9th, scoring 63 points in the first game. The Rebels’ defense allowed only 7 points, which ranks 4th.

Austin Simmons leads Ole Miss as quarterback, with 341 passing yards in one game. He has thrown three touchdowns and two interceptions. Running back Kewan Lacy added 108 rushing yards and three rushing touchdowns.

Wide receiver Harrison Wallace III made an impact with 130 receiving yards. He caught one touchdown in his first game. Tight end Dae’Quan Wright is questionable due to an injury, while Luke Hasz is out with an ankle injury.

Final Betting Pick

Ole Miss is a strong pick for the money line at -377. They are ranked 21st in the AP poll and 15th in the Coaches Poll. Their offense is impressive, scoring 63 points in their last game. This high-scoring ability makes them a reliable choice against Kentucky.

The over/under prediction of over 52.5 is supported by Ole Miss’s scoring power. They put up 63 points in their last game, and Kentucky’s defense allowed 16 points. With both teams having strong offensive and defensive stats, the total could easily surpass 52.5 points.

All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.