On Saturday, September 27, 2025, the Oregon Ducks will take on the Penn State Nittany Lions at Beaver Stadium in University Park, PA. This game is set to kick off at 7:30 PM and will be aired on NBC. Both teams are highly ranked, with Oregon holding a 4-0 record and Penn State at 3-0. The Ducks are ranked #6 in the AP poll, while the Nittany Lions are ranked #3.

Oregon vs. Penn State Betting Prediction

• Money Line Prediction: Oregon Ducks +138. Oregon has been strong on the road, winning their last six away games. Their offense is ranked high, and they have a perfect away record this season.
• Over/Under Prediction: Over 52.5. Both teams have been scoring well, and Oregon’s games have often gone over when the total is set at 50 or more.

Team Trends

• The Oregon Ducks are ranked #6 in the AP Poll and #5 in the Coaches Poll.
• Penn State Nittany Lions hold a perfect 3-0 home record this season.
• Oregon Ducks have a 4-0 record this season, with a 1-0 record on the road.
• Penn State’s defense has allowed only 17 points this season, ranking them 2nd in the nation.
• Oregon scored 203 points this season, placing them 5th in points for.

Oregon vs Penn State Preview

The Oregon Ducks are visiting Beaver Stadium with a 4-0 record. They are ranked #6 in the AP poll and #5 in the Coaches Poll. Oregon has shown strong performance on the road, winning their only away game this season. They are on a 4-game win streak, which includes a conference victory. Last season, they reached the College Football Playoff Quarterfinals but lost to Ohio State.

Penn State Nittany Lions are also undefeated with a 3-0 record. They hold the #3 spot in the AP poll and #2 in the Coaches Poll. All their wins have been at home, making Beaver Stadium a tough place for visitors. Penn State is coming off a close loss to Notre Dame in the last season’s College Football Playoff Semifinal. They are eager to maintain their strong start this season.

Penn State Nittany Lions Overview

Penn State Nittany Lions hold a strong position this season. They are ranked #3 in the AP poll and #2 in the Coaches Poll. The team plays in the Big Ten conference and calls Beaver Stadium their home.

The Nittany Lions have a perfect 3-0 record at home this season. They have not played any road games yet. Their last postseason game was a narrow loss to Notre Dame in the College Football Playoff Semifinal.

Drew Allar leads the team as the starting QB, with 626 passing yards and 4 touchdowns in three games. Nicholas Singleton and Kaytron Allen are key players in the running game. On defense, the team ranks 2nd in points allowed with only 17 points against them this season.

Oregon Ducks: Aiming for Victory on the Road

The Oregon Ducks are ranked #6 in the AP poll and #5 in the Coaches Poll. They belong to the Big Ten conference and play their home games at Autzen Stadium. This season, they have an impressive 4-0 record, with a 1-0 mark on the road.

Dante Moore leads the Ducks as the top quarterback. In four games, he has thrown for 962 yards and 11 touchdowns with just one interception. On the ground, Jayden Limar has rushed for 215 yards and scored three touchdowns.

The Ducks have scored 203 points this season, placing them 5th in the nation for points scored. On defense, they have allowed only 37 points, ranking 15th. Their last postseason game was a loss to Ohio State in the College Football Playoff Quarterfinal at the Rose Bowl.

Final Betting Pick

The Oregon Ducks are a solid pick for the money line at +138. They have been strong on the road, winning their last six away games. Their offense is ranked high, scoring 203 points this season, which is fifth in the nation. This strong offensive performance makes them a good choice for this game.

The over 52.5 is also a good bet. Oregon’s games often go over when the total is set at 50 or more. Both teams have shown they can score, with Oregon putting up 41 points against Oregon State and Penn State scoring 52 against Villanova. This scoring ability from both sides supports the over bet.

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All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.