Purdue Boilermakers vs Michigan Wolverines NCAAF Betting Prediction
PublishedOctober 28, 2025,            Posted By: Maria Uebelhor
Last updated:October 28, 2025 ,

NCAAF Purdue Boilermakers vs Michigan Prediction 11/1

The Purdue Boilermakers will take on the Michigan Wolverines in Week 10 of the 2025 regular season. The game is set for Saturday, November 1, 2025, at 7:00 PM at Michigan Stadium in Ann Arbor, MI. Fans can catch the action on BTN as these two Big Ten teams meet under the night sky.

Purdue vs. Michigan Betting Prediction

  • Money Line Prediction: Michigan Wolverines -1798. Michigan is unbeaten at home this season with a 4-0 record. They have a strong track record as favorites, winning 29 of their last 30 games in this role.
  • Over/Under Prediction: Over 49.5. Michigan’s games have gone over in 11 of their last 15 home games. Purdue’s games with totals of 50 or more have gone over in 18 of their last 29 games.

Team Trends

  • Michigan Wolverines are undefeated at home this season with a 4-0 record.
  • Purdue Boilermakers have not won any away games this season, holding a 0-3 road record.
  • Michigan Wolverines are ranked #21 in both the AP and Coaches Polls.
  • Purdue Boilermakers have a 0-5 record in conference play this season.
  • Michigan Wolverines have a strong rushing offense, ranked 12th in the nation with 1,794 yards.

Purdue vs Michigan Preview

The Purdue Boilermakers head to Ann Arbor with a 2-6 record. They are searching for their first road win of the season. The Boilermakers have struggled in conference play, holding a 0-5 record. They are looking to end a six-game losing streak. Purdue is unranked and sits at the bottom of the Big Ten standings.

The Michigan Wolverines enter the game with a 6-2 record. They are ranked 21st in both the AP and Coaches Polls. Michigan is strong at home with a perfect 4-0 record. They are on a two-game win streak and hold a 4-1 conference record. The Wolverines are fifth in the Big Ten standings and aim to continue their winning ways.

Michigan Wolverines: Home Stronghold and Stellar Players

Michigan Wolverines have a strong home record, standing at 4-0 this season. They play in the Big Ten Conference and host games at Michigan Stadium. The team currently holds a 6-2 overall record, with a 4-1 standing in their conference games.

Bryce Underwood leads the team as quarterback with 1,526 passing yards and seven touchdowns. Justice Haynes dominates as a running back with 857 rushing yards and ten touchdowns. On the receiving end, Donaven McCulley stands out with 378 receiving yards and two touchdowns.

On defense, Michigan has allowed 139 points this season, ranking 64th. They have recorded 22 sacks and 11 interceptions. Michigan’s last postseason game was the ReliaQuest Bowl, where they defeated Alabama Crimson Tide 19-13.

Purdue Boilermakers: Road Challenges and Player Standouts

Purdue Boilermakers have struggled on the road this season, with an 0-3 record. They are part of the Big Ten Conference and typically play their home games at Ross-Ade Stadium. This season, the Boilermakers have a 2-6 overall record, but they have not won any of their five conference games.

Ryan Browne is a key player for Purdue, leading the team with 1,689 passing yards and eight touchdowns. Devin Mockobee has been effective on the ground, rushing for 521 yards and scoring four touchdowns. Michael Jackson III is a reliable target with 398 receiving yards and one touchdown in eight games.

On defense, Purdue has allowed 222 points, which ranks them 113th. The team has recorded 19 sacks and two interceptions this season. Purdue is coming off a narrow 24-27 loss to Rutgers, and they are 21.0-point underdogs in their upcoming game against Michigan.

Final Betting Pick

Michigan has been strong at home, with a 4-0 record this season. They have won 29 of their last 30 games as favorites, making them a reliable pick for the money line. Their defense has been solid, allowing only 139 points this season, which ranks them 64th. This makes them a tough team to beat at home.

The over/under prediction of over 49.5 is also a good pick. Michigan’s home games have seen high scores, going over in 11 of their last 15 games. Purdue’s games with totals of 50 or more have gone over in 18 of their last 29 games. This trend suggests that both teams can contribute to a high-scoring game.

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All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.