On Saturday, October 4, 2025, the Vanderbilt Commodores will play against the Alabama Crimson Tide at Saban Field at Bryant-Denny Stadium in Tuscaloosa, AL. The game will start at 3:30 PM and be broadcast on ABC. Vanderbilt is entering the game with a 5-0 record, while Alabama has a 3-1 record this season. Both teams are part of the Southeastern Conference.

Vanderbilt vs. Alabama Betting Prediction

• Money Line Prediction: Alabama Crimson Tide -422. Alabama has a strong home record, winning their last 29 out of 30 home games. They are also ranked higher in both the AP and Coaches Polls.
• Over/Under Prediction: Over 56.5. Vanderbilt has hit the over in 13 of their last 18 games with totals of 50 or more. Both teams have shown they can score high points in recent games.

Team Trends

• Vanderbilt Commodores have a perfect 5-0 record this season, with a 2-0 record on the road.
• Alabama Crimson Tide holds a 3-1 record this season, with a 2-0 record at home.
• Vanderbilt is ranked #16 in the AP Poll and #17 in the Coaches Poll.
• Alabama is ranked #10 in the AP Poll and #11 in the Coaches Poll.
• The game will be played at Saban Field at Bryant-Denny Stadium in Tuscaloosa, AL.

Vanderbilt vs Alabama Preview

On October 4, 2025, the Vanderbilt Commodores will travel to Tuscaloosa to play against the Alabama Crimson Tide. Vanderbilt is undefeated this season with a 5-0 record. They are ranked #16 in the AP poll and #17 in the Coaches Poll. Alabama, with a 3-1 record, holds the #10 spot in the AP poll and #11 in the Coaches Poll. Both teams are in the Southeastern Conference.

Vanderbilt has shown strength on the road with a 2-0 record. Alabama has been strong at home, winning both of their home games this season. The game will be played at Saban Field at Bryant-Denny Stadium. It will be an afternoon game, starting at 3:30 PM, and will be shown on ABC. Both teams are looking to improve their conference records, which currently stand at 1-0 for each team.

Alabama Crimson Tide: Dominant at Home

The Alabama Crimson Tide is ranked #10 in the AP Poll and #11 in the Coaches Poll. They compete in the Southeastern Conference and play at Saban Field at Bryant-Denny Stadium. The team has a strong start with a 3-1 record this season, including a perfect 2-0 at home.

Ty Simpson leads the quarterbacks with 1,138 passing yards and 11 touchdowns in four games. Kevin Riley, the top running back, has rushed for 150 yards and caught 12 passes for 114 yards. Germie Bernard stands out among wide receivers, with 20 receptions for 310 yards and four touchdowns.

Alabama’s offense ranks 25th in passing yards with 1,287 yards and has scored 152 points this season. Their defense is solid, allowing 66 points while recording six sacks and three interceptions. The team is strong at home, with a 29-1 record over the last 30 home games.

Vanderbilt Commodores: Road Warriors

Vanderbilt holds a perfect 5-0 record this season. They are ranked #16 in the AP Poll and #17 in the Coaches Poll. The team plays in the Southeastern Conference.

Diego Pavia leads Vanderbilt’s quarterbacks with 1,211 passing yards and 13 touchdowns. Sedrick Alexander is the top running back, rushing for 243 yards and scoring four touchdowns. Junior Sherrill stands out among wide receivers with 17 receptions and five touchdowns.

Vanderbilt’s offense is ranked 16th in passing yards, totaling 1,355 yards this season. Their defense has allowed 86 points, recorded 14 sacks, and has three interceptions. The team won their last game against Utah State, 55-35.

Final Betting Pick

Alabama is a strong pick for the money line at -422. They have a solid home record, winning 29 of their last 30 home games. This shows they play well at Saban Field, making them a reliable choice.

The over 56.5 is a good choice because Vanderbilt often hits the over in games with totals of 50 or more. They have done this in 13 of their last 18 games. Both teams have shown they can score a lot, which supports the over pick.

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All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.