The Baltimore Ravens will take on the Buffalo Bills on Sunday, September 7, 2025. The game will be held at Highmark Stadium in Orchard Park, NY, and is scheduled for 8:20 PM. Fans can catch all the action on NBC.
Ravens vs. Bills Betting Prediction
- Money Line Prediction: Ravens -101. The Ravens have been strong in preseason, winning all three games. They have shown a solid defense, ranking 2nd in opponent score. This gives them an edge against the Bills at home.
- Over/Under Prediction: Under 51.5 (-109). Both teams have strong defenses. The Ravens have allowed only 32 points in preseason, while the Bills have struggled to score consistently.
Team Trends
- The Buffalo Bills will play at Highmark Stadium in Orchard Park, NY, for their Week 1 game.
- John Harbaugh is the head coach of the Baltimore Ravens.
- The Baltimore Ravens won all three of their preseason games in 2025.
- Sean McDermott is the head coach of the Buffalo Bills.
- The Buffalo Bills lost their only home preseason game in 2025 against the New York Giants.
Ravens vs Bills Preview
The Baltimore Ravens and Buffalo Bills are set to begin their 2025 season at Highmark Stadium. Lamar Jackson leads the Ravens with a strong projection of 220.7 passing yards and nearly two touchdowns. Derrick Henry is expected to add power to the Ravens’ ground game with 95.2 rushing yards. The Ravens’ defense will need to be ready for Josh Allen, who is projected to throw for 236.4 yards and 1.7 touchdowns.
For the Bills, James Cook is projected to gain 61.4 rushing yards, providing a balanced attack alongside Allen. The Bills’ receiving corps, including Khalil Shakir, looks to make an impact. Shakir is projected to catch 4.5 passes for 49.7 yards. With both teams eager to start the season strong, this game could be a key moment for setting the tone for the rest of the year.
Buffalo Bills: Home Team Overview
The Buffalo Bills are led by head coach Sean McDermott. The team plays in the AFC East and calls Highmark Stadium home. Under McDermott, the Bills have shown strong performance in recent seasons.
Josh Allen is the top quarterback for the Bills with a projection of 236.4 passing yards in this game. James Cook leads the running backs with an expected 61.4 rushing yards. Khalil Shakir is a key wide receiver, though he is currently questionable with an ankle injury.
Last season, the Bills ranked 2nd in scoring, with 525 total points. They were 9th in both passing and rushing yards, showing balance on offense. On defense, the Bills finished 11th in opponent scoring, with 368 points allowed.
Ravens Ready for Action
Lamar Jackson leads the Baltimore Ravens as quarterback. He is expected to throw for 220.7 yards and score 1.8 touchdowns. The Ravens play under head coach John Harbaugh, calling M&T Bank Stadium their home.
Derrick Henry is the main running back, with a projection of 95.2 rushing yards. Zay Flowers is a top receiver, expected to catch for 58.5 yards. Tight end Mark Andrews might add 47.3 yards with 0.4 touchdowns.
Last season, the Ravens ranked 3rd in scoring, with 518 points. They were 7th in passing yards and 1st in rushing yards. On defense, the Ravens ranked 9th in opponent scoring, allowing 361 points.
Final Betting Pick
The Ravens have shown strong performance in the preseason, winning all their games. They have a defense that ranks 2nd in opponent score, allowing only 32 points. This solid defense gives them an advantage against the Bills, who have struggled to score consistently.
For the over/under prediction, the total is set at 51.5. Both teams have strong defenses, with the Ravens allowing just 32 points in the preseason. The Bills have had trouble scoring, which makes the under a reasonable choice for this game.
All odds are courtesy of Action247 Sportsbook. Good luck!!
* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.
Last updated:August 27, 2025 Baltimore Ravens, Buffalo Bills