The Cleveland Browns will play against the Detroit Lions on Sunday, September 28, 2025. The game will take place at Ford Field in Detroit, MI, starting at 1:00 PM. Fans can catch the action on FOX.

Browns vs. Lions Betting Prediction

• Money Line Prediction: Detroit Lions -483. The Lions have a strong home record this season at 1-0. They have shown solid offensive stats, ranking high in both passing and rushing yards.
• Over/Under Prediction: Over 44.5 (-107). Both teams have shown the ability to score points, with the Lions scoring over 30 points in their last two games.

Team Trends

• The Detroit Lions have a strong home record this season, winning their only home game so far against the Chicago Bears 52-21.
• The Cleveland Browns have struggled on the road, losing their only away game this season to the Baltimore Ravens 41-17.
• Jared Goff of the Lions threw for 334 yards and 5 touchdowns in their home win against the Bears.
• The Browns’ recent win was a close 13-10 victory against the Green Bay Packers at home.
• The Lions’ running game was strong in their win against the Ravens, with 224 rushing yards.

Browns vs Lions Preview

The Cleveland Browns will visit the Detroit Lions in an exciting Week 4 game of the 2025 NFL season. The Browns hold a 1-2 record, placing them at the bottom of the AFC North. Meanwhile, the Lions stand at 2-1, sitting third in the NFC North. Both teams aim to improve their standings with a win at Ford Field.

Joe Flacco leads the Browns with a projection of 236.5 passing yards and 1.5 touchdowns. On the other side, Jared Goff is expected to throw for 262.5 yards and 2 touchdowns for the Lions. Key players like Jahmyr Gibbs and Amon-Ra St. Brown will play crucial roles for Detroit, while Quinshon Judkins and Jerry Jeudy look to make an impact for Cleveland. Fans can watch the game on FOX at 1:00 PM on Sunday.

Detroit Lions: Gearing Up for the Game

The Detroit Lions have a strong start this season with a 2-1-0 record. Head Coach Dan Campbell is leading the team in the NFC North division. They will play at home in Ford Field, where they are undefeated so far.

Jared Goff is the top quarterback for the Lions, with projections of 262.5 passing yards and 2 touchdowns for this game. Jahmyr Gibbs is the leading running back, expected to gain 75.2 rushing yards. Amon-Ra St. Brown is a key wide receiver, projected to get 78 receiving yards and 0.6 touchdowns.

Last season, the Lions ranked first in scoring with 564 points. They were second in passing yards and sixth in rushing yards. The team is dealing with several injuries, including key players like Marcus Davenport and Malcolm Rodriguez, who are currently out.

Cleveland Browns: Ready for the Road Challenge

The Cleveland Browns hold a 1-2-0 record this season under Head Coach Kevin Stefanski. They are part of the AFC North division. The team has faced challenges on the road, with a 0-1-0 record away from home.

Joe Flacco leads the Browns as their top quarterback. He is expected to throw for 236.5 yards and score 1.5 touchdowns in this game. Running back Quinshon Judkins is projected to rush for 67.1 yards and score 0.6 touchdowns.

Jerry Jeudy is a key receiver for the Browns, with a projection of 66 receiving yards. Tight end David Njoku is also important, expected to gain 39.7 yards. Several players are out with injuries, including Deshaun Watson and Jeremiah Owusu-Koramoah.

Final Betting Pick

The Detroit Lions are a strong pick for the money line at -483. They have been solid at home with a 1-0 record. Jared Goff leads the offense with projected 262.5 passing yards and 2 touchdowns, which can help them control the game.

The over 44.5 points is also a good choice. The Lions have scored over 30 points in their last two games. The Browns have shown they can score, with Joe Flacco projected for 236.5 passing yards and 1.5 touchdowns. This suggests a high-scoring game is likely.

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All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.