Philadelphia Eagles vs Kansas City Chiefs NFL Betting Prediction
PublishedSeptember 10, 2025,            Posted By: Maria Uebelhor
Last updated:September 10, 2025 ,

NFL Eagles vs Kansas City Chiefs Prediction 9/14

Get ready for an exciting NFL game as the Philadelphia Eagles take on the Kansas City Chiefs on Sunday, September 14, 2025. The game will be held at Arrowhead Stadium in Kansas City, MO, starting at 4:25 PM. You can catch all the action on FOX.

Eagles vs. Chiefs Betting Prediction

  • Money Line Prediction: Philadelphia Eagles -117. The Eagles have a strong start this season with a win against the Cowboys. Their rushing game, led by Saquon Barkley, looks solid. The Chiefs lost their opener and might struggle against the Eagles’ defense.
  • Over/Under Prediction: Under 46.5 (-106). Both teams have strong defenses, with the Eagles allowing only 20 points in their last game. The Chiefs also have a top-ranked defense, which might keep the score low.

Team Trends

  • The Philadelphia Eagles won their first game of the season against the Dallas Cowboys with a score of 24-20.
  • Kansas City Chiefs lost their first game of the season to the Los Angeles Chargers, 27-21.
  • Philadelphia Eagles’ head coach is Nick Sirianni, while the offensive coordinator is Kevin Patullo.
  • Kansas City Chiefs’ head coach is Andy Reid, and Matt Nagy serves as the offensive coordinator.
  • The game will be played at Arrowhead Stadium, the home field of the Kansas City Chiefs.

Eagles vs Chiefs Preview

The Philadelphia Eagles and Kansas City Chiefs will meet in Week 2 of the 2025 NFL season. The Eagles come into this game with a 1-0 record, while the Chiefs are looking to bounce back from a loss. This game at Arrowhead Stadium will test the Chiefs’ resolve as they aim to climb up the AFC West standings.

Jalen Hurts leads the Eagles with a projected 206.5 passing yards and 21.2 fantasy points. On the other side, Patrick Mahomes is expected to throw for 237 yards and earn 17.9 fantasy points. The Eagles’ Saquon Barkley is set to rush for 97.4 yards, while Isiah Pacheco of the Chiefs is projected to gain 47.6 yards on the ground. Both teams will rely on their key players to make an impact in this important game.

Chiefs Ready for Action at Arrowhead

The Kansas City Chiefs are led by head coach Andy Reid. They play at Arrowhead Stadium and are part of the AFC West. Their current season record stands at 0-1-0.

Quarterback Patrick Mahomes is a key player for the Chiefs. In their last game, he threw for 258 yards and one touchdown. Mahomes ranks 9th in passing yards and 10th in passing touchdowns for the season.

Isiah Pacheco leads the running game with 25 rushing yards. Marquise Brown is the top wide receiver with 99 receiving yards. Travis Kelce adds strength with two receptions for 47 yards and one touchdown.

Eagles Fly into Kansas City

The Philadelphia Eagles come in with head coach Nick Sirianni leading the way. They play in the NFC East and have a season record of 1-0-0. Quarterback Jalen Hurts is ready to make an impact, with projections of 206.5 passing yards and 1.3 touchdowns in this game.

Running back Saquon Barkley will be key for the Eagles’ ground game. He is projected to rush for 97.4 yards and score 0.7 touchdowns. A.J. Brown is expected to lead the receiving unit with 72.1 yards and 0.5 touchdowns.

Dallas Goedert is a vital part of the offense as the top tight end. He is projected to have 42.9 receiving yards. Jake Elliott will handle the kicking duties, with expectations of making 1.6 field goals.

Final Betting Pick

The Eagles’ money line at -117 is a good pick. They started the season strong with a win over the Cowboys. Jalen Hurts is projected to throw for over 200 yards, and Saquon Barkley is expected to rush for nearly 100 yards. The Chiefs lost their opener and might find it hard to break through the Eagles’ defense, which ranks high in several categories.

The under 46.5 points is also a solid choice. Both teams have strong defenses. The Eagles allowed only 20 points in their last game. The Chiefs have a top-ranked defense, as well. This could keep the score low, making the under a good bet.

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All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.