The Jacksonville Jaguars will play against the Denver Broncos on Sunday, December 21, 2025. The game is set to take place at Empower Field at Mile High in Denver, CO, with kickoff at 4:05 PM. Fans can catch the action on FOX as these two AFC teams meet under overcast skies.

Jaguars vs. Broncos Betting Prediction

• Money Line Prediction: Denver Broncos -168. The Broncos are strong at home with a 7-0 record. Their defense ranks third in opponent score, which gives them an edge.
• Over/Under Prediction: Under 45.5. Both teams have solid defenses, and the Broncos’ home games often have lower scores.

Team Trends

• The Denver Broncos have an impressive home record of 7-0 this season.
• Jacksonville Jaguars have a strong road record of 4-2 this season.
• Denver Broncos’ quarterback, Bo Nix, threw for 302 yards and 4 touchdowns in their last home game against the Green Bay Packers.
• Jacksonville Jaguars’ Trevor Lawrence threw for 330 yards and 5 touchdowns in their recent win against the New York Jets.
• The game will be played at Empower Field at Mile High, where the weather is forecasted to be very cold with overcast clouds.

Jaguars vs Broncos Preview

The Jacksonville Jaguars are heading into Week 16 with a solid 10-4 record, leading the AFC South. They have a five-game winning streak and are looking to maintain their momentum. Quarterback Trevor Lawrence is expected to pass for 216.9 yards and throw 1.4 touchdowns. Running back Travis Etienne Jr. aims to add 60.1 rushing yards and 0.4 touchdowns to his season stats.

Meanwhile, the Denver Broncos are at the top of the AFC West with a 12-2 record. They have an impressive 11-game winning streak and are undefeated at home. Quarterback Bo Nix is projected to pass for 211.1 yards with 1.7 touchdowns. Running back RJ Harvey is expected to contribute 50.9 rushing yards and 0.6 touchdowns. Both teams are ready to battle in the cold, overcast conditions at Empower Field.

Denver Broncos: Dominant at Home

The Denver Broncos are having a strong season with a 12-2 record. They are undefeated at home with a 7-0 record. Sean Payton, the head coach, has guided the team in the AFC West.

Bo Nix leads the team as quarterback, with 3,256 passing yards and 23 touchdowns this season. RJ Harvey contributes as the top running back with 419 rushing yards and six touchdowns. Courtland Sutton is the leading wide receiver with 886 receiving yards and six touchdowns.

The Broncos excel in defense, ranking first in sacks with 63. The team allows only 311 points against them, placing them third in the league. They face some injuries, including J.K. Dobbins, who will miss the rest of the season with a foot injury.

Jacksonville Jaguars: Road Warriors Ready for Battle

The Jacksonville Jaguars, led by head coach Liam Coen, have a 10-4 record this season. They have performed well on the road with a 4-2 record. Trevor Lawrence is their top quarterback, achieving 3,210 passing yards and 23 touchdowns over 14 games.

Travis Etienne Jr. is the leading rusher for the Jaguars, with 949 rushing yards and seven touchdowns. Brian Thomas Jr. stands out as a key wide receiver with 601 receiving yards and two touchdowns. Cam Little, their kicker, has successfully made 23 field goals this season.

The Jaguars’ defense ranks 15th in sacks with 34, and they have six interceptions. However, they have allowed 435 points, placing them 25th. Several players are on the injury report, including Bhayshul Tuten and Travis Hunter, who are out for the rest of the season.

Final Betting Pick

The Denver Broncos have a perfect home record of 7-0. Their strong defense ranks third in opponent score, which makes them a solid pick on the money line at -168. Playing at home gives them an advantage, as they have not lost there this season.

The over/under prediction is under 45.5 points. The Broncos’ home games often have lower scores, and both teams have strong defenses. The Jaguars have shown solid defensive play, which might keep the total score low.

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All odds are courtesy of Action247 Sportsbook. Good luck!!

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* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.