The Carolina Panthers will play against the New England Patriots on Sunday, September 28, 2025. The game will take place at Gillette Stadium in Foxborough, MA, and is scheduled for 1:00 PM. Fans can catch the action on FOX. Both teams have a 1-2 record this season.

Panthers vs. Patriots Betting Prediction

• Money Line Prediction: Panthers +198. The Panthers have shown strong offensive performances, especially in their recent win against the Falcons. The Patriots have struggled at home, with a 0-2 record this season.
• Over/Under Prediction: Under 43.5. Both teams have had games with lower scoring totals, and the Panthers’ defense recently held the Falcons scoreless.

Team Trends

• The Carolina Panthers have a road record of 0-2-0 this season.
• The New England Patriots have not won at home this season, with a home record of 0-2-0.
• In Week 3, the Panthers won against the Atlanta Falcons with a score of 30-0 at home.
• The Patriots lost their last home game in Week 3 against the Pittsburgh Steelers with a score of 21-14.
• The Panthers’ head coach is Dave Canales, while the Patriots’ head coach is Mike Vrabel.

Panthers vs Patriots Preview

The Carolina Panthers will visit the New England Patriots in Week 4 of the 2025 NFL season. Both teams hold a 1-2 record, making this game important for getting back on track. The Patriots are currently second in the AFC East, while the Panthers are second in the NFC South.

Quarterbacks Bryce Young and Drake Maye will lead their teams on the field. Young is projected to pass for over 200 yards, while Maye is expected to throw for more than 220 yards. The Panthers’ Chuba Hubbard and the Patriots’ Rhamondre Stevenson will be key players in the running game. Fans can watch the game on FOX at 1:00 PM from Gillette Stadium.

Patriots at Home: Key Insights

The New England Patriots, led by head coach Mike Vrabel, are playing at Gillette Stadium. Their current season record is 1-2-0. They have a strong division record of 1-0-0 but are looking for their first home win.

Drake Maye is the top quarterback for the Patriots. He has 785 passing yards and five touchdowns so far this season. He is projected to add 224.4 passing yards and 1.6 touchdowns in the next game.

Rhamondre Stevenson leads the running backs with 87 rushing yards and 138 receiving yards in three games. Hunter Henry is a top tight end with 165 receiving yards and two touchdowns. On the injury front, several players are out, including Jahlani Tavai and Yasir Durant.

Carolina Panthers: Road Challenges and Key Players

The Carolina Panthers, led by head coach Dave Canales, have faced tough games on the road this season. Their record stands at 1-2-0, with both losses coming away from Bank of America Stadium. They are eager for a win to break their road losing streak.

Bryce Young is the starting quarterback for the Panthers. He has thrown for 603 yards and four touchdowns in three games. In the next game, he is projected to gain 204.4 passing yards and 1.3 touchdowns.

Chuba Hubbard is a key player in the backfield. He has 168 rushing yards this season and is expected to add 64 rushing yards in the upcoming game. The team faces injury challenges, with several players like Austin Corbett and Robert Hunt out for multiple games.

Final Betting Pick

The Panthers’ money line at +198 looks favorable. They recently shut out the Falcons 30-0, showing strong defense. Bryce Young, their quarterback, is projected to throw for over 200 yards. The Panthers have struggled on the road, but the Patriots have not won at home this season. This gives the Panthers a good chance to win.

The under 43.5 is a solid choice. The Panthers’ defense held the Falcons scoreless, and the Patriots have had low-scoring games at home. Both teams have offenses that can struggle, making a low total likely. The Panthers’ defense will aim to keep the Patriots’ scoring low, supporting the under bet.

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All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.