Seattle Seahawks vs Arizona Cardinals NFL Betting Prediction

NFL Seattle Seahawks vs Arizona Cardinals Prediction 9/25

The Seattle Seahawks will play against the Arizona Cardinals on Thursday, September 25, 2025. The game will take place at State Farm Stadium in Glendale, AZ, with kickoff at 8:15 PM. Fans can catch the action on AMZN under a clear sky, as the retractable roof will likely keep the very hot day from affecting play. Both teams enter the game with a 2-1 record this season.

Seahawks vs. Cardinals Betting Prediction

  • Money Line Prediction: Seattle Seahawks -119. The Seahawks have shown strength on the road, winning their only away game this season. Their recent win against the Saints with a 44-13 score also highlights their current form.
  • Over/Under Prediction: Over 43.5 (-108). Both teams have offenses capable of putting up points. The Seahawks scored 44 points in their last game, and the Cardinals have a solid offensive record, suggesting a higher scoring game.

Team Trends

  • The Arizona Cardinals have a perfect home record this season, winning their only home game against the Carolina Panthers.
  • Seattle Seahawks have an undefeated away record this season, winning their only road game against the Pittsburgh Steelers.
  • The Seattle Seahawks scored 44 points in their last game, defeating the New Orleans Saints 44-13.
  • Arizona Cardinals lost their last game by just one point, falling to the San Francisco 49ers 16-15.
  • Both the Seahawks and Cardinals have identical season records so far, standing at 2-1-0.

Seahawks vs Cardinals Preview

The Seattle Seahawks are ready to take on the Arizona Cardinals in an exciting Week 4 game. Both teams have a 2-1 record and are looking to climb the NFC West standings. The game will be held at State Farm Stadium, where the retractable roof will keep the very hot weather at bay.

Sam Darnold leads the Seahawks with a projected 235 passing yards and 1.5 touchdowns. Kenneth Walker III is expected to contribute on the ground with 56.8 rushing yards. The Cardinals have Kyler Murray at quarterback, projected to throw for 215.2 yards and score 1.3 touchdowns. Trey Benson is set to add to the ground game with 65.1 rushing yards. Fans can expect a competitive game from these two teams.

Arizona Cardinals: Key Players and Stats

The Arizona Cardinals have a 2-1 record this season. Head Coach Jonathan Gannon leads the team, aiming to improve their division record. They play at the State Farm Stadium and belong to the NFC West division.

Kyler Murray, the team’s quarterback, is expected to gain 215.2 passing yards with 1.3 touchdowns in the upcoming game. Trey Benson leads the rushing attack with a projected 65.1 yards. Marvin Harrison Jr. is a key receiver, projected to have 56.7 receiving yards.

Last season, the Cardinals ranked 12th in scoring with 400 points. Their defense ranked 14th by allowing 379 points. They also recorded 41 sacks, which was 8th in the league.

Seattle Seahawks: Key Players and Insights

Sam Darnold is the starting quarterback for the Seattle Seahawks. In this game, he is expected to throw for 235 yards and 1.5 touchdowns. His performance will be crucial for the team’s success.

Kenneth Walker III is leading the Seahawks’ running game. He is expected to gain 56.8 rushing yards and score 0.6 touchdowns. Walker’s ability to break through defenses will be important.

Jaxon Smith-Njigba is a top receiver for Seattle. He is projected to have 79.2 receiving yards and 0.4 touchdowns. Head Coach Mike Macdonald will rely on his offense to secure a win against the Cardinals.

Final Betting Pick

The Seattle Seahawks are a strong pick for the money line at -119. They have shown success on the road, winning their only away game this season against the Pittsburgh Steelers, 31-17. Their recent 44-13 win over the Saints also highlights their ability to score and dominate games.

The over 43.5 points is a good choice given both teams’ offensive capabilities. The Seahawks scored 44 points in their last game, showing they can put up points quickly. The Cardinals also have a solid offense, with Kyler Murray leading the way, suggesting a high-scoring game is likely.

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All odds are courtesy of Action247 Sportsbook. Good luck!!


* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.