Cleveland Guardians vs Baltimore Orioles MLB Betting Prediction

MLB Cleveland Guardians vs Baltimore Orioles Prediction 4/16

On Wednesday, April 16, 2025, the Cleveland Guardians will visit the Baltimore Orioles at Oriole Park at Camden Yards. The game is set to start at 6:35 PM under the lights. Fans can look forward to an exciting evening of baseball.

Guardians vs. Orioles Betting Prediction

  • Money Line Prediction: Guardians MoneyLine: 110. The Guardians have a better record this season and a strong home performance. Their recent win against the Orioles gives them momentum.
  • Over/Under Prediction: Under 8.5 (-113). Both teams have struggled with consistent hitting, and Gavin Williams has shown solid pitching for the Guardians.

Team Trends

  • The Cleveland Guardians have a strong home record of 5-1 this season.
  • Baltimore Orioles are 3 games back in the AL East with a 6-10 record.
  • Logan Allen from the Cleveland Guardians had a solid performance on April 15th, allowing no runs in 5 2/3 innings.
  • Steven Kwan hit a home run and had 3 RBIs against the Baltimore Orioles on April 15th.
  • The Baltimore Orioles’ Cedric Mullins had a home run and 2 RBIs on April 8th against the Arizona Diamondbacks.

Guardians vs Orioles Preview

The Cleveland Guardians will take on the Baltimore Orioles at Oriole Park at Camden Yards on Wednesday evening. Gavin Williams will start for the Guardians. In his recent game against the White Sox, Williams pitched five innings and allowed just one run. His season ERA sits at 3.46, showing his ability to keep runs low.

Dean Kremer will be on the mound for the Orioles. He has struggled this season, with an ERA of 8.16. In his last outing against the Diamondbacks, Kremer gave up six runs in less than five innings. Both teams will look to their pitchers to set the tone for the game.

Orioles’ Key Players and Performance Overview

Cedric Mullins is having a strong start to the season. He has played in 15 games with a batting average of .300. Mullins leads the league and team in home runs, runs, and RBIs. Adley Rutschman is another important player for the Orioles. He has a batting average of .237 and has hit three home runs. Rutschman ranks second on the team in home runs and runs. Tyler O’Neill has also contributed well to the team. He has a batting average of .265 and has hit two home runs. O’Neill ranks second on the team in RBIs and fourth in runs.

Cleveland Guardians: Players and Pitching Insights

The Guardians have some strong hitters this season. Steven Kwan is leading with a .333 batting average. He also ranks first in the league for runs and RBIs. Kwan has hit three home runs, placing him second on the team. Kyle Manzardo has hit four home runs, leading the team and league. His batting average is .176, but he shares the top spot in RBIs with Kwan. Manzardo’s on-base percentage is .312, showing his ability to get on base. José Ramírez has also been effective at the plate. He has hit four home runs and ranks second in RBIs. His batting average stands at .250, and he has scored six runs this season.

Final Betting Pick

The Guardians have a solid home record this season, which supports the MoneyLine prediction. They are 5-1 at home, showing they play well in their own stadium. Gavin Williams has been effective on the mound, with a 3.46 ERA and no home runs allowed in his recent games. This makes the Guardians a strong pick against the Orioles.

The Under 8.5 prediction is also supported by the teams’ hitting struggles. The Guardians have a .229 batting average, while the Orioles are at .234. Both teams have not shown consistent hitting, which could lead to a low-scoring game. With Gavin Williams’ solid pitching, the Under looks like a good choice.


All odds are courtesy of Action247 Sportsbook. Good luck!!


* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.