The Houston Astros (88-73) travel to face off against the Cleveland Guardians (92-69) on Sunday, September 29th. This game will be played at Progressive Field in Cleveland and televised on BSGL. The Astros are coming off a win in their previous game, while the Guardians are looking to get back on track from a loss to the Astros. First pitch is set for 2:10 CT.

Astros vs. Guardians Betting Prediction

• Money Line Prediction: Astros (+153)
• Over/Under Prediction: Over 7.5 Runs

• The Astros have won 6 of their last 10 games, showing strong recent form.
• In the last 15 games, the Astros have outscored their opponents 86 to 77, indicating a potent offense.
• The Astros have a 4-1 record against the Guardians this season, demonstrating head-to-head dominance.
• In their last 5 road games, the Astros have a 4-1 record, indicating strong away performance.
• The Astros have scored 5 or more runs in 8 of their last 15 games, showcasing consistent offensive production.

Astros vs Guardians

It was a low-scoring game in the most recent game of this Astros vs. Guardians series. Houston went into the matchup as +130 underdogs and squeaked out a 4-3 win. The Astros had a three-run 2nd inning and didn’t score another run until putting up the game’s go-ahead run in the top of the 9th. As for the Guardians, they scored one run in the 3rd inning and tied the game with a run in the 5th, but couldn’t push across another run.

Justin Verlander got the win for the Astros, going six innings and giving up three earned runs. He finished the game with five strikeouts but issued zero walks. As for the Guardians, Ben Lively got the start and took the loss, giving up two earned runs in four innings of work.

Mauricio Dubon, Zach Dezenzo, and Kyle Tucker each had two hits for the Astros’ offense. Dubon and Dezenzo each scored two runs, while Tucker drove in a run. Jose Ramirez did a bit of everything for the Guardians, going 2/3 with a home run and three RBIs.

Heading into today’s game, the Astros are 88-73 overall and have won two straight games. They lead the AL West by four games over the Mariners. Houston’s series record this season is 27-22-2, and their run line record is 83-78. As the underdog, they are 28-15 on the run line.

This season, the over has hit in 76.4% of Astros games, with an average of 8.6 runs per game. When the total is set at 7.5 runs, their over/under record is 11-20. The O/U line for their games has averaged 8 runs per game.

Ryan Gusto Gets The Start For The Astros

For today’s game against the Guardians, the Astros will rely on Ryan Gusto to set the tone. It’s his debut for the season and he’s looking to put together a strong start in his debut.

Astros Offense Breakdown

Heading into today’s game, the Astros are averaging 4.6 runs per game, which is 10th in the league. They have been even better at home, averaging 4.9 runs per game. Overall, the Astros are the league’s 2nd best hitting team, with a team batting average of .262. Houston’s offense has been very good at avoiding strikeouts this season, as they are 3rd in the league in fewest strikeouts per game.

Yordan Alvarez has been the Astros’ top power threat this season, as his 35 homers are the best on the team and 8th in the league. Alex Bregman has been swinging a hot bat of late, going 11/34 in his last nine games with three homers.

Today, the Guardians are looking to avoid a sweep by the Astros after dropping the first two games of the series. Cleveland’s overall series record this season is 29-16-6, and their run line record is 82-79, with an average run margin of 0.5 runs per game. As underdogs, they are 36-25 against the run line, with an average run margin of 3.3 runs.

Cleveland’s straight-up record as favorites is 64-36, and their overall record is 92-69, giving them a six-game lead in the AL Central. The under has hit in their last five games, and their O/U record for the season is 68-82. This season, their games have averaged 8.3 runs, and 68.9% of their games have had totals higher than today’s line of 7.5 runs.

Nick Sandlin Gets The Start For The Guardians

Cleveland is starting Nick Sandlin today, and he has made 68 appearances out of the bullpen this season. Sandlin’s only start came on September 27th, where he went 1 2/3 innings, giving up four hits and issuing two walks. He didn’t give up a run in that outing. Sandlin has finished with a no-decision in each of his last four outings. Looking back further, he has finished with a no-decision in six of his last seven outings. Sandlin’s ERA for the season is 3.75, and he has a record of 8-0.

Guardians Offense Breakdown

Over his last nine games, José Ramírez has been on fire for the Guardians, going 13/34 with four home runs and 11 RBIs. For the season, he is batting .279 with 39 home runs and 118 RBIs, which is 3rd in the MLB. Josh Naylor is also having a strong season for the Guardians, as he is batting .243 and has gone deep 31 times.

As a team, the Guardians are averaging 4.4 runs per game and are 11th in the league in home runs. They are batting just .238 this season and have the league’s worst BABIP. Cleveland is also near the bottom of the league in on-base percentage and OPS.

Astros vs Guardians Prediction

Given the payout, we really like the Astros on the money line today. Our predicted final score is 5-4 in favor of the Astros, and with the payout for an Astros win sitting at +153, this is the route we recommend going.

If you’re looking for a potential parlay, you could look to pair an Astros win with the over. However, our prediction is that this one will stay under the 7.5 run line.

---

All odds are courtesy of Action247 Sportsbook. Good luck!!

---

* All odds are provided by Action247 Sportsbook and all odds subject to change.**All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk.Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.