San Diego Padres vs San Francisco Giants MLB Betting Prediction

MLB San Diego Padres vs San Francisco Giants Prediction 6/4

The San Diego Padres will visit the San Francisco Giants at Oracle Park on Wednesday, June 4, 2025. This night game is set to begin at 9:45 PM. Fans can catch the action on the SDPA channel. The Padres hold a 35-24 record, while the Giants are at 33-28 this season.

Padres vs. Giants Betting Prediction

  • Money Line Prediction: San Diego Padres at -109. The Padres have a strong division record of 9-1 and have won the last two games against the Giants. Their away record is slightly above .500, which gives them an edge.
  • Over/Under Prediction: Under 7.0. Both teams have strong pitching, with the Padres’ Nick Pivetta having an ERA of 2.74 and the Giants’ Kyle Harrison at 2.51. Recent games between these teams have been low-scoring.

Team Trends

  • The San Diego Padres have a road record of 15-14 this season.
  • The San Francisco Giants have a home record of 17-11 this season.
  • The Padres recently won two consecutive games against the Giants, with scores of 3-2 and 1-0.
  • Manny Machado went 4 for 4 with 2 RBIs in the Padres’ recent 3-2 win over the Giants.
  • The Giants’ Logan Webb pitched 8 scoreless innings in their recent 1-0 loss to the Padres.

Padres vs Giants Preview

The San Diego Padres and the San Francisco Giants are set to meet at Oracle Park. The Padres have a strong record of 35-24, while the Giants hold a 33-28 record. This game is part of the National League West division. Fans can expect an exciting evening of baseball.

Nick Pivetta will take the mound for the Padres. He has an ERA of 2.74 and a WHIP of 1.01. Kyle Harrison will start for the Giants. He has an ERA of 2.51 and a WHIP of 0.98. Both pitchers have shown strong performances this season, making this a key matchup to watch.

San Francisco Giants: Key Players and Performance

The San Francisco Giants have some notable hitters this season. Matt Chapman leads the team with 10 home runs and 30 runs, both ranking first on the team. His batting average is .236, and his on-base percentage is .357. Wilmer Flores is another key player for the Giants. He has played 60 games with a batting average of .253. Flores leads the team in RBIs with 47 and has hit 10 home runs. Kyle Harrison will be the starting pitcher for the Giants in the upcoming game. Harrison’s ERA is 2.51, and his WHIP is 0.98. He has a win-loss record of 1-1 this season.

San Diego Padres: A Look at the Lineup

The San Diego Padres have several standout players this season. Manny Machado has a batting average of .315 over 59 games. He has hit 7 home runs and leads the team with 40 runs. Gavin Sheets is another key player for the Padres. He has played 56 games with a batting average of .260. Sheets leads the team with 11 home runs and 34 RBIs. Nick Pivetta will take the mound for the Padres in the upcoming game. His ERA is 2.74, and his WHIP is 1.01. Pivetta has a win-loss record of 6-2 this season.

Final Betting Pick

The Padres are a solid pick for the money line at -109. They have a strong division record of 9-1 and have won the last two games against the Giants. Their away record is slightly above .500, which gives them confidence on the road.

The under 7.0 is a good choice for this game. Both starting pitchers, Nick Pivetta for the Padres and Kyle Harrison for the Giants, have low ERAs. Recent games between these teams have been low-scoring, with the last two games ending 3-2 and 1-0 in favor of the Padres.


All odds are courtesy of Action247 Sportsbook. Good luck!!


* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.