The Detroit Lions will face off against the San Francisco 49ers at 8:15 ET on Monday, December 30th. This matchup is being played at Levi’s Stadium in Santa Clara.

The 49ers are the underdog at +164 on the money line as they host the Lions on Monday, December 30th at 8:15 ET on ABC. The Lions are favored on the road with a money line of -196 and a point spread of -3.5. This week 17 NFC matchup is being played at Levi’s Stadium, and the over/under line is set at 50.5 points.

• Date: Monday, December 30th
• Time: 8:15 ET
• Location: Levi’s Stadium, Santa Clara
• TV: ABC

Lions vs 49ers

With a 13-2 record, the Lions sit atop both the NFC North and our NFL power rankings. They have a 76.3% chance of winning the division and are a lock for the playoffs. Detroit is 7-0 on the road this season, including a 34-17 win over the Bears in week 16.

Against the spread, the Lions are 10-4-1, with an average scoring margin of +12.9 points per game. Their O/U record is 8-6-1, with the over hitting in three straight games.

Heading into week 17, the 49ers rank 9th in our power rankings despite their 6-9 record and two-game losing streak. After a week 14 win over the Bears, they’ve dropped two straight, including a 29-17 loss to the Dolphins in week 16. San Francisco was favored by 1.5 points in that game but couldn’t get the win at home.

With the 49ers out of the playoff race, they have a 0.0% chance of making the postseason. They are 5-10 against the spread this season, with an average scoring margin of -1.2 points per game. Their O/U record stands at 8-7, with their games averaging 45.3 points per game.

Lions Injury Report

• Kyle Peko – Pectoral (Out)
• Kalif Raymond – Foot (Out)
• Graham Glasgow – Knee (Questionable)
• Jalen Reeves-Maybin – Neck (Questionable)
• Alex Anzalone – Forearm (Out)
• Carlton Davis – Jaw (Out)
• Marcus Davenport – Elbow (Out)
• Michael Badgley – Hamstring (Out)
• David Montgomery – Knee (Out)
• John Cominsky – Knee (Out)
• Netane Muti – Shoulder (Out)
• Khalil Dorsey – Leg (Out)
• Derrick Barnes – Knee (Out)
• Alim McNeill – Knee (Out)
• Malcolm Rodriguez – Knee (Out)
• Aidan Hutchinson – Tibia (Out)
• Antoine Green – Concussion (Out)
• Mekhi Wingo – Knee (Out)
• Ennis Rakestraw Jr. – Hamstring (Out)
• Connor Galvin – Knee (Out)
• Nate Lynn – Shoulder (Out)

49ers Injury Report

• Kevin Givens – Pectoral (Out)
• Dre Greenlaw – Calf (Questionable)
• George Odum – Knee (Out)
• Jon Feliciano – Knee (Out)
• Trent Williams – Ankle (Questionable)
• Christian McCaffrey – Knee (Out)
• Javon Hargrave – Triceps (Out)
• De’Vondre Campbell Sr. – Suspension (Out)
• Ben Bartch – Ankle (Out)
• Mitch Wishnowsky – Back (Out)
• Brandon Aiyuk – Knee (Out)
• Jaylon Moore – Quadriceps (Questionable)
• Curtis Robinson – Knee (Out)
• Elijah Mitchell – Hamstring (Out)
• Aaron Banks – Knee (Questionable)
• Darrell Luter Jr. – Pelvis (Out)
• Robert Beal Jr. – Ankle (Questionable)
• Jordan Mason – Ankle (Out)
• Drake Jackson – Knee (Out)
• Isaac Guerendo – Foot/hamstring (Questionable)
• Tatum Bethune – Knee (Out)
• Mason Pline – Undisclosed (Out)

Lions Offense Breakdown

Jared Goff has been on a tear for the Lions, throwing for 336 yards and 3 touchdowns in week 16, following his 494-yard, 5-touchdown performance in week 15. He posted a passer rating of 136 against the Bears, completing 23 of 32 passes. Jameson Williams led the receiving corps with 5 catches for 143 yards, while Jahmyr Gibbs rushed for 109 yards on 23 carries.

Detroit enters week 17 ranked 3rd in our offensive power rankings. They lead the NFL in scoring, averaging 32.9 points per game, and are 2nd in passing yards with 264.7 per game. The Lions also rank 5th in 3rd-down conversions, with a 46.7% success rate.

49ers Offense Breakdown

Heading into week 17, the 49ers are 16th in the NFL in points per game, averaging 22.1, and they rank 14th in our offensive power rankings. They are 8th in the league in yards per game (365.7) and 7th in passing yards per game (235.7), despite ranking 21st in passing attempts. San Francisco is 10th in rushing, with 130 yards per game, on 27.4 attempts per contest. They are 10th in the NFL in 3rd-down conversion rate (42%) and 21st in red zone conversion percentage.

Brock Purdy threw for 313 yards (26/40) with 2 touchdowns and an interception in week 16 against Miami. George Kittle had 8 catches for 106 yards, and Purdy led the team in rushing with 26 yards on 4 carries. San Francisco scored 7 points in the 4th quarter after being shut out in the 1st and 3rd quarters.

Lions Team Defense

In their 34-17 win over the Bears, the Lions’ defense allowed just 59 rushing yards on 17 attempts. Despite giving up 323 passing yards, Detroit held Chicago to 20% on third down and limited them to 17 points. The Lions’ defense recorded two sacks and had two more quarterback hits than their opponents.

Detroit’s defense gave up 382 total yards, but the Bears were unable to establish a running game, averaging only 3.5 yards per attempt. Although the Bears found some success through the air, the Lions tightened up on key downs and limited Chicago to 17 points in the game.

49ers Team Defense

In their most recent game, the 49ers’ defense gave up 381 yards in a 29-17 loss to the Dolphins. They struggled to stop the run, allowing 166 rushing yards on just 30 attempts, which is an average of 5.5 yards per attempt. Despite this, they did hold the Dolphins to a 33.3% conversion rate on third down.

San Francisco’s defense didn’t record any sacks in the game and they also lost the QB hit differential by a margin of -5. In the passing game, they allowed 215 yards, with Miami completing 64.7% of their passes and averaging 6.3 yards per attempt.

Lions vs 49ers Trends

• The Lions are 4-1 ATS in their last road games and 5-0 straight-up.
• Through their last three home games, San Francisco has an ATS record of just 0-3. However, their overall record was 0-3 while averaging 12 points per game.
• As the betting underdog, the 49ers have an ATS mark of just 0-3 in their last three games. San Francisco posted a straight up mark of 0-3 in these matchups.
• In their last five games as the betting favorite, the Lions have a straight up record of 4-1, while going 2-2-1 against the spread.

Lions vs 49ers Prediction

For this week 17 matchup between the 49ers and Lions, we have the 49ers coming out on top by a score of 27-22. With the point spread sitting at -3.5 in favor of the 49ers, our pick against the spread is to take the 49ers to cover as home underdogs.

As for the over/under, with the line at 50.5 points, we are leaning towards the under, with our projected combined score coming in at 49 points.

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All odds are courtesy of Action247 Sportsbook. Good luck!!

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* All odds are provided by Action247 Sportsbook and all odds subject to change.**All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk.Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.