The San Francisco 49ers will face off against the Miami Dolphins at 4:25 ET on Sunday, December 22nd. This matchup is being played at Hard Rock Stadium in Miami Gardens.

The 49ers are the underdog with a point spread of +1.5 as they face the Dolphins on Sunday, December 22nd at 4:25 ET on CBS. The Dolphins are favored with a money line of -123, and the over/under line is set at 46 points. This non-conference matchup is being played at Hard Rock Stadium in Miami Gardens, FL. The 49ers need to add their record, and the Dolphins’ record is not included.

• Date: Sunday, December 22nd
• Time: 4:25 ET
• Location: Hard Rock Stadium, Miami Gardens
• TV: CBS

49ers vs Dolphins

Heading into week 16, the 49ers sit at 6-8, putting them 4th in the NFC West. This includes a 1-4 division record and a 2-4 mark on the road. Our power rankings have San Francisco 7th, but they have just a 0.1% chance of making the playoffs. After a 25-point win over the Bears in week 14, the 49ers couldn’t keep it going at home, losing 12-6 to the Rams in week 15.

Against the spread, the 49ers are 5-9, with a -0.4 scoring margin. They are 5-7 as favorites and 0-2 as underdogs. Their O/U record is 7-7, with their games averaging 45.3 points compared to a 46.5-point line.

Heading into week 16, the Dolphins sit 15th in our power rankings and have a 4.9% chance of making the playoffs. Miami is 6-8 on the season, which puts them 2nd in the AFC East. In conference play, they are 5-5, and they have a 4-3 record at home compared to 2-5 on the road.

Against the spread, the Dolphins are 5-9 and have failed to cover in three straight games. They have a scoring margin of -2.6 points per game. Their O/U record is 6-8, with their games averaging 42 points compared to an average line of 45.1.

49ers Injury Report

• Trent Williams – Ankle (Questionable)
• Jon Feliciano – Knee (Out)
• Christian McCaffrey – Knee (Out)
• Javon Hargrave – Triceps (Out)
• De’Vondre Campbell Sr. – Suspension (Out)
• Kevin Givens – Pectoral (Out)
• Dre Greenlaw – Achilles (Questionable)
• George Odum – Knee (Out)
• Mitch Wishnowsky – Back (Out)
• Ambry Thomas – Forearm (Out)
• Elijah Mitchell – Hamstring (Out)
• Drake Jackson – Knee (Out)
• Curtis Robinson – Knee (Out)
• Ben Bartch – Ankle (Out)
• Khalil Davis – Knee (Questionable)
• Brandon Aiyuk – Knee (Out)
• Ji’Ayir Brown – Groin (Questionable)
• Jordan Mason – Ankle (Out)
• Darrell Luter Jr. – Pelvis (Out)
• Dee Winters – Neck (Questionable)
• Malik Mustapha – Chest/shoulder (Questionable)
• Tatum Bethune – Knee (Out)

Dolphins Injury Report

• Grayson Murphy – Knee (Out)
• Tahj Washington – Undisclosed (Out)
• Tanner Conner – Undisclosed (Out)
• Cam Smith – Shoulder (Out)
• Cameron Goode – Undisclosed (Questionable)
• Grant DuBose – Head (Questionable)
• Dee Eskridge – Knee (Questionable)
• Anthony Schwartz – Knee (Out)
• Jaylen Waddle – Knee (Questionable)
• Jaelan Phillips – Knee (Out)
• Kion Smith – Knee (Out)
• Austin Jackson – Knee (Out)
• Cam Brown – Knee (Out)
• Blake Ferguson – Personal (Questionable)
• Terron Armstead – Knee (Questionable)
• Kendall Lamm – Back (Questionable)
• Tyus Bowser – Knee/calf (Out)
• Braxton Berrios – Knee (Out)
• Bradley Chubb – Knee (Questionable)

49ers Offense Breakdown

San Francisco’s offense ranks 14th in our power rankings, averaging 22.4 points per game, which is 13th in the NFL. They are 8th in the league in yards per game with 365.1, and they focus on the run game, ranking 7th in both rushing attempts and yards per game. On 3rd down, they convert 42.3% of the time, which is 10th in the league, but their red zone conversion rate is 17.6%, placing them 20th.

Brock Purdy struggled in week 15, posting a passer rating of 45 after going 14/31 for 142 yards and 1 interception. George Kittle led the team with 61 receiving yards, and Isaac Guerendo had 57 rushing yards on 16 carries. The 49ers scored 3 points in the 1st quarter and 3rd quarter but were shut out in the 2nd and 4th quarters against the Rams.

Dolphins Offense Breakdown

Heading into week 16, the Dolphins rank 19th in our offensive power rankings, averaging 19.7 points per game, which places them 21st in the NFL. They are 19th in passing yards per game (222.6) and 14th in passing attempts, with 35 per game. On the ground, Miami ranks 24th in rushing yards per game, averaging 101.4 yards on 26.3 attempts.

Tua Tagovailoa threw for 196 yards and a touchdown in week 15, but he also had 3 interceptions, finishing with a passer rating of 60. Malik Washington led the team with 5 catches for 52 yards, and De’Von Achane had 41 rushing yards on 12 carries. Miami struggled in the 4th quarter, failing to score against the Texans.

49ers Team Defense

In their 12-6 loss to the Rams, the 49ers’ defense gave up 142 rushing yards on 38 attempts, but they did hold the Rams to just 26.7% on third down. The 49ers allowed just 160 yards through the air and limited the Rams to 5.9 yards per attempt in the passing game. However, they were unable to record any sacks and allowed the Rams to control the ball on the ground.

The 49ers’ defense also won the QB hit battle, with two more hits than the Rams, but they did have a -4 differential in tackles for loss. Despite their struggles against the run, the 49ers’ defense kept them in the game by not allowing a touchdown through the air.

Dolphins Team Defense

In their 20-12 loss to the Texans, the Dolphins’ defense allowed just 104 passing yards but gave up two passing touchdowns. Houston finished with 181 total yards, with Miami limiting them to 77 yards on 20 rushing attempts. The Dolphins’ defense also recorded four sacks and held Houston to 38.5% on third down conversions. Despite this, the Dolphins still allowed the Texans to come away with two passing touchdowns.

49ers vs Dolphins Trends

• When looking at their past ten road matchups, San Francisco has an ATS record of 4-6 while averaging 25 per game. The team went 5-5 overall in these games.
• In their last five games at home, the Dolphins have a straight up record of 1-4 while going 2-3 vs the spread. The team’s offense averaged 17 points per game in these contests.
• Spanning across their last five games as the betting underdog, the 49ers have gone 1-4 vs the spread. Their overall record in these games was 1-4.
• In their last ten games as the betting favorite, the Dolphins have a straight up record of 7-3 and an ATS mark of 5-5.

49ers vs Dolphins Prediction

Our model has the 49ers coming out on top by a score of 25-22 in their week 16 matchup against the Dolphins. With the point spread sitting at -1.5 in favor of the 49ers, we like them to cover as the road favorites.

For this one, we also like the over as a strong play, with the line currently at 46 points and our projections forecasting a combined score of 47 points.

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All odds are courtesy of Action247 Sportsbook. Good luck!!

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* All odds are provided by Action247 Sportsbook and all odds subject to change.**All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk.Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.