week 16 commanders vs 49ers nfl football betting

NFL Week 16: Commanders vs 49ers & Eagles vs Cowboys

NFL Regular Season Week 16 Betting Outlook

We are seeing many teams getting ready for the playoffs as we head into the final weeks of the NFL regular season. Some teams are starting to take the lead, while others fall into the background. 

This next week, there are many games that are up in the air. You never know what will happen heading into each game. Many times, the underdogs can surprise you and come out ahead.

It is Week 16, with just three more weeks of regular season football on the schedule. The games mean more, the wins and losses are now deciding playoff spots, and the intensity of the betting is at a season-high. Here are the NFL matchups for Christmas weekend.

 All odds and lines are courtesy of Action247 Sportsbook.


Washington Commanders at San Francisco 49ers – Saturday, December 24th, 2022 4:05 pm CST 

Sunday night was a tough loss for the Commanders. Having dropped that game to the Giants, even as Washington is currently in a playoff spot, it is going to be tough to stay there with their closing schedule. That begins this week as touchdown underdogs at the 49ers.

San Francisco has clinched the NFC West, and they still have a shot at moving up to the No. 2 seed. And this is happening with Brock Purdy at quarterback and without Deebo Samuel, who is still a couple of weeks away from returning.


Philadelphia Eagles at Dallas Cowboys – Saturday, December 24th, 2022 4:25 pm CST 

week 16 eagles vs cowboys nfl football betting

Dallas’s loss to the Jaguars takes some of the luster from their Christmas Eve game against the Eagles. The Cowboys are slight favorites (-1.5), but even if they win, they will only be within two games of Philadelphia, with only two games to play.

Throughout the loss to Jacksonville, the Cowboys’ offense was still great. And Jalen Hurts and the Eagles as the second-highest-scoring team in the league. The total points line of 51.5 is going to be tested by these two high-scoring teams.


* All odds provided by Action247 Sportsbook and all odds subject to change.
**All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk.

nfl action247 insider betting odds