The Chicago Cubs will take on the Milwaukee Brewers in Game 1 of the NLDS. This game will be held at American Family Field in Milwaukee, WI, on Saturday, October 4, 2025, at 2:08 PM. Fans can catch the action on TBS as the Cubs and Brewers begin their best-of-5 series under a clear sky. The Cubs finished the regular season with a 92-70 record, while the Brewers had a 97-65 record.

Cubs vs. Brewers Betting Prediction

• Money Line Prediction: Milwaukee Brewers at -155. The Brewers have a strong home record of 52-29 and a solid pitching advantage with Freddy Peralta’s 2.70 ERA.
• Over/Under Prediction: Under 7.5 at -121. Both teams have strong starting pitchers, and the Brewers’ pitching ranks second in ERA, suggesting a low-scoring game.

Team Trends

• The Chicago Cubs have a regular season road record of 42-39.
• The Milwaukee Brewers finished the regular season with a home record of 52-29.
• In their last game against the San Diego Padres, the Cubs won 3-1 with 13 hits and 1 home run.
• The Brewers won their last regular season game against the Cincinnati Reds 4-2, with Danny Jansen hitting a home run.
• Game 1 of the NLDS will be played at American Family Field in Milwaukee under clear skies.

Cubs vs Brewers Preview

The Chicago Cubs are ready to challenge the Milwaukee Brewers in Game 1 of the NLDS. The Cubs ended their season with a solid 92-70 record. Their starting pitcher, Matthew Boyd, brings an ERA of 3.21 and a WHIP of 1.09. Boyd’s performance will be key as the Cubs aim to gain an early edge in the series.

On the other side, the Milwaukee Brewers finished the regular season with a 97-65 record. Freddy Peralta will take the mound for the Brewers. He has an impressive ERA of 2.70 and a WHIP of 1.07. With the game set at American Family Field, the Brewers hope to capitalize on their home advantage. Fans can watch the game on TBS at 2:08 PM.

Milwaukee Brewers: Key Players and Stats

The Milwaukee Brewers have been strong at the plate this season. Brice Turang leads the team with a .288 batting average and has played 156 games. He also tops the team in home runs with 18 and runs with 97. William Contreras is another key player for the Brewers. He has a batting average of .260 and has played 150 games. Contreras is second on the team in home runs with 17 and runs with 89. On the mound, Freddy Peralta is the starting pitcher for this game. He has an ERA of 2.70 and a WHIP of 1.07. Peralta’s record stands at 17 wins and 6 losses, making him a reliable option for the Brewers.

Chicago Cubs: Aiming for Victory

The Chicago Cubs have some strong hitters this season. Michael Busch stands out with a .261 batting average. He leads the team with 34 home runs and has scored 78 runs. Seiya Suzuki is another key player for the Cubs. He has a batting average of .245 and has hit 32 home runs. Suzuki also leads the team with 103 RBIs. On the pitching side, Matthew Boyd will start for the Cubs. His ERA is 3.21, and he has a WHIP of 1.09. Boyd’s record is 14 wins and 8 losses.

Final Betting Pick

The Milwaukee Brewers have a strong case for the money line at -155. Their home record of 52-29 shows they play well at American Family Field. Freddy Peralta’s 2.70 ERA gives them a pitching edge. Peralta’s performance this season, with a 17-6 record, adds confidence to this pick.

For the over/under prediction, taking the under 7.5 at -121 seems reasonable. Both teams have solid starting pitchers, with Peralta and Matthew Boyd both having ERAs under 3.30. The Brewers’ pitching ranks second in ERA, which supports a low-scoring game. This indicates a potential for fewer runs scored in this game.

All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.