The Pittsburgh Pirates will take on the St. Louis Cardinals on Wednesday, August 27, 2025, at Busch Stadium. The game is set to start at 7:45 PM and will be broadcast on SN PT. The weather forecast predicts an overcast sky with a calm crosswind, making it a warm evening for baseball. The Pirates hold a record of 58-75, while the Cardinals have a record of 65-68.

Pirates vs. Cardinals Betting Prediction

• Money Line Prediction: Pittsburgh Pirates +156. The Pirates have been strong in their recent games, winning four of their last five. They also won against the Cardinals 8-3 in the previous game, showing good form on the road.
• Over/Under Prediction: Over 7.5 (-101). Both teams have shown the ability to score runs, with the Pirates scoring 8 and the Cardinals 7 in their recent games against each other. The starting pitchers have mid-range ERAs, which could lead to more runs.

Team Trends

• The Pittsburgh Pirates have a road record of 19-45 this season.
• St. Louis Cardinals have a home record of 36-31 this season.
• The Pirates recently won against the Cardinals 8-3 on August 26, 2025.
• The Cardinals won a close game against the Pirates 7-6 on August 25, 2025.
• Weather for the game at Busch Stadium is forecasted to be overcast with calm crosswinds.

Pirates vs Cardinals Preview

On Wednesday evening, the Pittsburgh Pirates are set to play the St. Louis Cardinals at Busch Stadium. The Pirates have a record of 58-75 and are in fifth place in their division. They recently won their last game and have a 6-4 record in their last ten games. Meanwhile, the Cardinals hold a 65-68 record and are in fourth place. They lost their last game and have a 4-6 record in their last ten games.

Carmen Mlodzinski will start for the Pirates. He has a 3.89 ERA and a 3-7 record this season. The Cardinals will have Sonny Gray on the mound. Gray has a 4.33 ERA and a 12-6 record. The weather forecast suggests an overcast sky with calm winds, making it a warm night for baseball.

Cardinals Ready for Action

The St. Louis Cardinals have some strong hitters this season. Willson Contreras is leading the team with 19 home runs. He also has a batting average of .259 and 73 RBIs.

Alec Burleson is another key player for the Cardinals. He has a batting average of .291 and has hit 16 home runs. Burleson has also scored 47 runs, helping the team in many games.

On the mound, Sonny Gray will start for the Cardinals. He has a record of 12 wins and 6 losses. Gray’s ERA stands at 4.33, showing his ability to perform under pressure.

Pirates Prepare for Battle

Andrew McCutchen is a key player for the Pirates. He has hit 12 home runs and has a batting average of .241. McCutchen has also scored 42 runs and leads the team in RBIs with 49. Isiah Kiner-Falefa is another important player for Pittsburgh. He has played in 115 games this season. Kiner-Falefa has a batting average of .267 and has scored 39 runs. Carmen Mlodzinski will pitch for the Pirates. He has an ERA of 3.89 and a record of 3 wins and 7 losses. Mlodzinski’s WHIP is 1.30, showing his ability to keep runners off base.

Final Betting Pick

The Pirates have been performing well on the road, winning four of their last five games. They recently defeated the Cardinals 8-3, showing strong hitting with 11 hits and four extra-base hits. Andrew McCutchen and Bryan Reynolds have been key players, contributing to the team’s recent success. The over 7.5 runs is a solid pick for this game. Both teams have shown they can score, with the Pirates scoring 8 and the Cardinals scoring 7 in their recent games. The starting pitchers, Carmen Mlodzinski and Sonny Gray, have mid-range ERAs, which could lead to more runs being scored in this game.

All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.