The Detroit Pistons will take on the Chicago Bulls at the United Center on Wednesday, October 22, 2025, at 8:00 PM. Both teams are starting the NBA regular season with fresh records of 0-0. Fans can catch the game on CHSN.

Pistons vs. Bulls Betting Prediction

• Spread Prediction: Bulls +4.0 (-108). The Bulls had a better preseason record at 3-2 and are playing at home, which might give them an edge to cover the spread.
• Over/Under Prediction: Under 233 (-110). With limited data on both teams’ scoring, taking the under seems safer as teams might start the season with lower scoring games.

Team Trends

• The NBA regular season is just starting, and both the Pistons and Bulls have a 0-0 record.
• The game will be held at the United Center in Chicago.
• Fans can watch the game on the CHSN channel.
• The game is scheduled for Wednesday, October 22, 2025, at 8:00 PM.
• This is the first game for both teams in the new season.

Pistons vs Bulls Preview

The Detroit Pistons are ready to take on the Chicago Bulls at the United Center. Both teams are looking to start the season strong. The Pistons’ lineup features Cade Cunningham at point guard, supported by Caris LeVert and Ausar Thompson. Tobias Harris and Isaiah Stewart will add depth in the forward positions.

On the other side, the Bulls have Josh Giddey leading the backcourt. Kevin Huerter and Isaac Okoro will join him to add scoring power. Matas Buzelis and Nikola Vučević will be key players in the frontcourt. Fans can watch the game on CHSN at 8:00 PM.

Chicago Bulls Ready to Begin the Season

The Chicago Bulls are set to start their NBA season at the United Center. The team looks to make a strong impression in their opening game. Playing at home gives them an edge with the support of their fans. The Bulls have worked hard in the offseason to prepare for this moment. They aim to improve their performance from last season. The players are eager to show their skills and teamwork on the court. The game against the Detroit Pistons marks a fresh start for the Bulls. It is a chance to set the tone for the rest of the season. Fans will be watching closely to see how the team performs in this opening game.

Detroit Pistons Aim to Start Strong

The Detroit Pistons enter the new season with determination. Head Coach J.B. Bickerstaff leads the team from the Eastern Conference’s Central Division. They finished the preseason with a 2-2 record, showing they can compete both at home and away. Cade Cunningham stands out as a key player for the Pistons. In the preseason, he averaged 20.7 points and 7.3 assists per game. The team will rely on his skills to guide them on the court against the Bulls. Injuries might affect the Pistons’ lineup. Jaden Ivey is out with knee discomfort, while Marcus Sasser is doubtful with a hip issue. Caris LeVert is probable and could play despite knee soreness.

Final Betting Pick

The Bulls’ preseason record of 3-2 shows they might have a slight advantage playing at home. This makes the Bulls +4.0 spread a solid pick. Playing at the United Center could give them the boost needed to cover the spread against the Pistons.

With both teams starting the season, scoring might be lower. This makes the Under 233 a good choice. Early season games often have teams still finding their rhythm, leading to fewer points.

All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change.**All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk.Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.