The Ohio Bobcats will take on the #12 Louisville Cardinals on Saturday, November 15, 2025, at 12:00 PM ET. The game will be held at the KFC Yum! Center in Louisville, KY. This non-conference matchup will be broadcast on CW, with the Louisville Cardinals as the favorite.

Ohio vs. Louisville Betting Prediction

• Spread Prediction: Ohio +31.5. Ohio has struggled this season, but a spread of +31.5 is large. Louisville is strong, but Ohio might keep it closer than expected.
• Over/Under Prediction: Over 175.5. Louisville scores 102 points per game, and Ohio’s defense might allow a high-scoring game.

Team Trends

• The game will take place at the KFC Yum! Center in Louisville, KY.
• Ohio Bobcats are the underdog with a spread of +31.5.
• Louisville Cardinals are favored with a moneyline of -100000.
• Ohio Bobcats have a straight-up record of 1-2 in their last 3 games.
• Louisville Cardinals have won all their last 3 games straight up.

Ohio vs Louisville Preview

The Ohio Bobcats will travel to Louisville to play against the #12 Louisville Cardinals on Saturday, November 15, 2025. The game is set for 12:00 PM ET at the KFC Yum! Center. The Cardinals are the favorites, and the game will be shown on CW.

Ohio comes into this game with a 1-2 record in the 2026 season. They recently lost to Saint Mary’s Gaels by 30 points. Meanwhile, Louisville holds a strong 3-0 record, with their latest win being against Kentucky Wildcats by 8 points. The Bobcats face a tough challenge against a top-ranked team.

Louisville Cardinals: Strong Start at Home

The Louisville Cardinals are off to a strong start this season. They hold a 3-0 record, all at home. This shows their ability to protect their home court. In their recent games, the Cardinals scored over 100 points twice. They defeated the South Carolina State Bulldogs by 59 points and the Jackson State Tigers by 36 points. Their high-scoring offense is a key part of their success. Key players like Mikel Brown Jr. and Ryan Conwell have been important. Brown Jr. scored 29 points against the Kentucky Wildcats. Conwell also contributed with 24 points in the same game.

Ohio Bobcats: Seeking Improvement on the Road

The Ohio Bobcats have had a mixed start to their season. They currently hold a 1-2 record. Their only win came at home against Illinois State, where they won by four points. On the road, the Bobcats have struggled, losing their only away game to Saint Mary’s by 30 points. Their offense has averaged 72.3 points per game. Jackson Paveletzke has been a standout player, averaging 18 points per game. The Bobcats’ shooting has room for improvement. Their three-point percentage is low at 25.9%. They will need better shooting to compete against strong teams like Louisville.

Final Betting Pick

Ohio has a challenging task against Louisville, but the +31.5 spread might be a good pick. Ohio’s offense scores 72.3 points per game, which is not high, but they can keep the game closer. Louisville is strong, but Ohio might cover the spread.

The over 175.5 is another solid pick. Louisville scores 102 points per game, which is among the best. Ohio’s defense might struggle, allowing for a high-scoring game. This could push the total over the set line.

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All odds are courtesy of Action247 Sportsbook. Good luck!!

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* All odds are provided by Action247 Sportsbook and all odds subject to change.**All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk.Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.