The Colorado Buffaloes will take on the TCU Horned Frogs in Week 6 of the 2025 regular season. This game is set for Saturday, October 4, 2025, at 7:30 PM at Amon G. Carter Stadium in Fort Worth, TX. Fans can catch the action on FOX. Both teams are part of the Big 12 Conference, making this a key game for both sides. The Buffaloes are looking to improve their 2-3 record, while the Horned Frogs aim to build on their 3-1 start.

Colorado vs. TCU Betting Prediction

• Money Line Prediction: TCU -576. TCU has a strong home record this season at 2-0. They have also been successful as favorites, winning their last 7 games in that position.
• Over/Under Prediction: Over 59.5. Both teams have shown they can score, with TCU averaging 149 points and Colorado 129 points this season. The trends also show a tendency for high-scoring games when the total is set at 50 or more.

Team Trends

• Colorado Buffaloes have a road record of 0-1 this season.
• TCU Horned Frogs are undefeated at home with a 2-0 record this season.
• Colorado Buffaloes rank 3rd in interceptions with 2 this season.
• TCU Horned Frogs have scored 149 points this season, ranking 35th.
• The game will be played at Amon G. Carter Stadium in Fort Worth, TX.

Colorado vs TCU Preview

The Colorado Buffaloes are set to visit the TCU Horned Frogs in Week 6 of the 2025 season. This is a night game at Amon G. Carter Stadium. Colorado, with a 2-3 record, is eager to bounce back from a recent loss. They have yet to win on the road this season. Their conference record stands at 0-2, placing them near the bottom of the Big 12 standings.

On the other side, TCU enters the game with a 3-1 record. They have performed well at home, winning both games played there. However, they are also coming off a loss and have a 0-1 conference record. TCU ranks higher in the conference standings than Colorado, but both teams are unranked nationally. The game will be broadcast on FOX, offering fans a chance to see how these teams stack up against each other.

TCU Horned Frogs Home Performance

The TCU Horned Frogs have shown strong performance at home this season. They have a home record of 2-0, which highlights their ability to perform well in their own stadium. Their overall record this season stands at 3-1, showing a solid start.

Josh Hoover is a standout player for the team. As the quarterback, he has played in four games with impressive stats. His passing yards total 1,242, and he has thrown 11 touchdowns so far.

The Horned Frogs’ offense has put up 149 points this season, ranking them 35th. Their defense has allowed 86 points, ranking them 54th. They have also recorded 12 sacks, placing them 9th in that category.

Colorado Buffaloes Road Challenges

The Colorado Buffaloes hold a road record of 0-1 this season. They play in the Big 12 conference and call Folsom Field their home stadium. Currently, their overall season record is 2-3, with a conference record of 0-2.

Kaidon Salter leads the team as quarterback. He has thrown for 684 yards and five touchdowns in four games. Salter’s performance ranks him 103rd in passing yards this season.

On the ground, Micah Welch stands out with 210 rushing yards over five games. Simeon Price and DeKalon Taylor also contribute to the running game. However, both Price and Taylor are listed as questionable due to injuries.

Final Betting Pick

TCU is a solid pick for the money line at -576. They have a strong home record this season, winning both home games. TCU has also won their last seven games as favorites, showing consistency in this role.

The over 59.5 is a good choice for this game. Both teams have shown they can score, with TCU averaging 149 points and Colorado 129 points this season. Trends indicate high-scoring games when the total is set at 50 or more, making the over a reasonable bet.

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All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.