The Michigan State Spartans will take on the Iowa Hawkeyes on Saturday, November 22, 2025. The game will be held at Kinnick Stadium in Iowa City, IA, with kickoff set for 3:30 PM. Fans can catch the action on FS1. This Week 13 game features the Spartans on the road with a 3-7 record against the Hawkeyes, who are 6-4 this season.

Michigan State vs. Iowa Betting Prediction

• Money Line Prediction: Iowa Hawkeyes -909. Iowa has a strong home record of 4-2 this season and a solid conference record. Michigan State is winless on the road, making Iowa the safer pick.
• Over/Under Prediction: Over 43.0. Both teams have shown the ability to score, and Iowa’s recent games have often gone over the total, making the over a viable option.

Team Trends

• Michigan State Spartans have not won any road games this season, with a record of 0-4.
• Iowa Hawkeyes have a strong home record this season, standing at 4-2.
• Michigan State has a conference record of 0-7 this season.
• Iowa Hawkeyes have scored 287 points this season, ranking them 50th in the nation.
• Michigan State’s defense ranks 4th in interceptions with 3 this season.

Michigan State vs Iowa Preview

The Michigan State Spartans are heading to Iowa City to play against the Iowa Hawkeyes. The Spartans have struggled this season with a 3-7 record and have not won on the road. They are 0-4 in away games and are looking to end a seven-game losing streak. Their conference record is 0-7, placing them near the bottom of the Big Ten standings.

On the other side, the Iowa Hawkeyes hold a 6-4 record and have been stronger at home, winning 4 out of 6 games. They sit in the middle of the Big Ten standings with a 4-3 conference record. However, they are also looking to bounce back from a two-game losing streak. The game at Kinnick Stadium will be crucial for both teams as they aim to improve their standings.

Hawkeyes at Home

The Iowa Hawkeyes play in the Big Ten Conference. Their home games are held at Kinnick Stadium. This season, they have a 6-4 overall record with a 4-2 record at home.

Mark Gronowski is the top quarterback for the Hawkeyes. He has played 10 games, passing for 1,216 yards and 6 touchdowns. Kamari Moulton leads the running backs with 612 rushing yards over 8 games.

In team stats, Iowa has scored 287 points, ranking 50th this season. Their defense has allowed 149 points, placing them 58th. The team has 19 sacks and 10 interceptions, which is among the top in the league.

Michigan State Spartans on the Road

Michigan State plays in the Big Ten Conference and holds their home games at Spartan Stadium. This season, they have a 3-7 overall record with a 0-4 record on the road. Their conference record stands at 0-7, reflecting a tough season.

Aidan Chiles is the top quarterback for the Spartans. He has played nine games, throwing for 1,392 yards and 10 touchdowns. His performance ranks him 107th in passing yards and 87th in passing touchdowns.

On the ground, Makhi Frazier leads the rushing attack with 520 yards in nine games. The team has scored 240 points this season, placing them 72nd in the league. Their defense has allowed 311 points, ranking them 120th.

Final Betting Pick

Iowa is a strong pick for the money line at -909. They have a solid home record of 4-2 this season. Playing at Kinnick Stadium gives them an advantage, especially against a Michigan State team that has not won on the road this year. Michigan State’s 0-4 road record shows their struggles away from home, making Iowa a safer choice.

The over 43.0 is a good option for this game. Iowa’s games have often gone over the total, and their offense ranks 50th in points scored. Michigan State’s defense has allowed 311 points this season, ranking 120th. This combination suggests that both teams can contribute to a higher-scoring game, supporting the over bet.

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All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.