In Week 10 of the 2025 regular season, the Oklahoma State Cowboys will play against the Kansas Jayhawks. The game will be held at David Booth Kansas Memorial Stadium in Lawrence, KS. Kickoff is scheduled for Saturday, November 1, 2025, at 4:00 PM and will be broadcast on ESPN+.

Oklahoma State vs. Kansas Betting Prediction

• Money Line Prediction: Kansas Jayhawks at -3063. Kansas has a better home record at 3-2 and a stronger overall season record compared to Oklahoma State’s 1-7. This makes Kansas the safer pick.
• Over/Under Prediction: Over 57.5. Both teams have shown a trend of games going over the total, especially Kansas with a 3-1 record in games with totals over 50 this season.

Team Trends

• Oklahoma State Cowboys have not won an away game this season, with a road record of 0-3.
• Kansas Jayhawks have a home record of 3-2 this season.
• Oklahoma State Cowboys have scored 116 points this season, ranking 103rd in points for.
• Kansas Jayhawks rank 40th in passing yards with 1980 yards this season.
• Oklahoma State Cowboys lost their last away game against Texas Tech Red Raiders with a score of 42-0.

Oklahoma State vs Kansas Preview

The Oklahoma State Cowboys will travel to face the Kansas Jayhawks in Week 10 of the 2025 season. The Cowboys have struggled this year with a 1-7 record. They have yet to win on the road. Their conference record stands at 0-5, and they are on a seven-game losing streak. This game is crucial for them to try and end their losing streak.

On the other hand, the Kansas Jayhawks hold a 4-4 record and are 2-3 in conference play. They have been stronger at home with a 3-2 record. However, they are on a two-game losing streak. Playing at home, they will look to improve their standing in the Big 12 conference. This game will be an opportunity for both teams to change their current streaks.

Key Players to Watch

The Kansas Jayhawks have a strong quarterback in Jalon Daniels. He has played in 8 games this season and thrown for 1881 yards, ranking 30th nationally. Daniels has also thrown 18 touchdowns, placing him 11th in the league.

Running back Leshon Williams is another standout player. Williams has accumulated 319 rushing yards over 8 games, ranking 189th in the nation. He has scored 5 rushing touchdowns, which is 81st among all players.

Wide receiver Emmanuel Henderson Jr. leads the team in receptions and receiving yards. Henderson has 34 receptions for 554 yards, putting him 45th in the league. He has scored 4 receiving touchdowns this season, ranking 64th nationally.

Team Performance and Stats

The Kansas Jayhawks play in the Big 12 Conference and have a current season record of 4-4. At home, they hold a record of 3-2, while their road record stands at 1-2. In conference play, they have won 2 games and lost 3.

Offensively, the team has scored 244 points this season, ranking 40th nationally. They have 1980 passing yards and 1225 rushing yards, placing them 40th and 62nd, respectively. The Jayhawks have also recorded 168 first downs, which is 29th in the nation.

On defense, Kansas has allowed 207 points, ranking 105th. They have been strong in creating turnovers with 4 interceptions and 5 fumbles recovered. The Jayhawks are effective in pressuring the quarterback, with 17 sacks, ranking 14th nationally.

Stadium and Betting Insights

The Kansas Jayhawks play their home games at the David Booth Kansas Memorial Stadium. They are currently favored by 24.5 points, and the total is set at 57.5. Despite coming off a 17-42 loss to Kansas State, the team has favorable betting trends.

Historically, the Jayhawks have performed well after a loss. In the last 23 games after a loss, they have a 17-6 record for over/under bets. They are also strong in home games, with a 16-8 record over the last 24 games.

As favorites, they have a 15-8 record in the last 23 games. In games with totals over 50, they have a 7-5 record in the last 12 games. Kansas is known for bouncing back, making them a team to watch in upcoming games.

Oklahoma State Cowboys Preview

Oklahoma State Cowboys have had a tough season, holding a record of 1-7. In conference games, they have yet to secure a victory, standing at 0-5. The team struggles both at home and on the road, with a home record of 1-4 and a road record of 0-3.

Quarterback Zane Flores is a key player for the Cowboys. Flores has thrown for 696 yards across 5 games, although he has not managed any touchdowns yet. He has 3 interceptions, ranking him 174th in the league.

Rodney Fields Jr. is the top running back, with 420 rushing yards in 6 games. He also has 1 touchdown and 19 receptions. However, Fields Jr. is questionable for the next game due to an undisclosed injury.

Final Betting Pick

Kansas is the safer pick for the money line at -3063. They have a better home record of 3-2 compared to Oklahoma State’s 0-3 road record. Kansas has also shown more strength this season with a 4-4 overall record, while Oklahoma State is struggling at 1-7.

The over/under prediction is set at 57.5, and taking the over seems reasonable. Kansas has a trend of games going over the total, especially in games with totals over 50. Oklahoma State’s defense has allowed a lot of points, which could lead to a high-scoring game. Both teams have shown they can score and allow points, making the over a solid choice.

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All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.