The Mississippi State Bulldogs will travel to Columbia, MO, to take on the Missouri Tigers on Saturday, November 15, 2025. This Week 12 game of the 2025 regular season kicks off at 7:45 PM ET at Faurot Field at Memorial Stadium. Fans can catch the action on SECN. Mississippi State enters with a 5-5 record, while Missouri stands at 6-3.

Mississippi State vs. Missouri Betting Prediction

• Money Line Prediction: Missouri Tigers -272. Missouri has a strong home record of 5-2 this season. They have not lost as a favorite in their last 22 games.
• Over/Under Prediction: Over 51.5. Mississippi State’s last three games as an underdog have all gone over. Missouri’s recent home games have also trended towards the over.

Team Trends

• Missouri Tigers have a home record of 5-2 this season.
• Mississippi State Bulldogs have a road record of 2-2 this season.
• Missouri Tigers rank 10th in rushing yards with 2096 yards this season.
• Mississippi State Bulldogs have 18 sacks, ranking 16th this season.
• Missouri Tigers are ranked #24 in the Coaches Poll.

Mississippi State vs Missouri Preview

The Mississippi State Bulldogs head to Missouri with a 5-5 record. They have struggled in conference play, holding a 1-5 record. On the road, they have split their games, standing at 2-2. The Bulldogs are looking to bounce back after a loss in their last game. They aim to improve their standing in the Southeastern Conference.

The Missouri Tigers are ranked 24th in the Coaches Poll. They have a 6-3 record and are coming off a two-game losing streak. At home, the Tigers have been strong with a 5-2 record. Missouri is looking to secure a win to strengthen their position in the conference standings. Both teams are eager to make a statement in this night game at Faurot Field.

Missouri Tigers: Season Overview and Key Players

The Missouri Tigers hold the #24 rank in the Coaches Poll. Their current season record stands at 6-3, with a strong home record of 5-2. Playing in the Southeastern Conference, the Tigers have a conference record of 2-3 this season.

Beau Pribula has been a standout quarterback for Missouri, with 1,690 passing yards and 11 touchdowns over eight games. However, he is currently out with an ankle injury. On the ground, Ahmad Hardy leads the team with 1,046 rushing yards and 12 touchdowns, making a significant impact in nine games.

On the receiving end, Kevin Coleman Jr. shines with 52 receptions and 559 receiving yards. Brett Norfleet, a key tight end, has caught five touchdowns this season. His status is questionable due to a shoulder injury, potentially affecting the team’s offensive lineup.

Mississippi State Bulldogs: Key Players and Season Insights

Mississippi State Bulldogs have a balanced season record of 5-5. They have won 3 games at home and 2 on the road. In conference play, they hold a 1-5 record, showing some challenges in the Southeastern Conference.

Blake Shapen is the main quarterback for the Bulldogs, with 2,237 passing yards and 15 touchdowns over 10 games. He has shown consistency in leading the offense. On the ground, Davon Booth has made contributions with 512 rushing yards and 7 touchdowns.

The team’s top receiver, Brenen Thompson, has 808 receiving yards and 6 touchdowns. Seydou Traore, a tight end, adds to the offense with 265 receiving yards and 4 touchdowns. These players are vital in the Bulldogs’ offensive strategy.

Final Betting Pick

The Missouri Tigers are favored at home with a strong record of 5-2 at Faurot Field. They have not lost as a favorite in their last 22 games, showing they perform well in expected wins. Missouri’s offense ranks 30th in points for, which supports their ability to secure a win against Mississippi State.

Mississippi State’s recent games as an underdog have all gone over the total, making the over 51.5 a solid pick. Their offense has shown they can score, ranking 20th in points for this season. Missouri’s home games have also trended towards the over, making this a good choice for bettors.

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All odds are courtesy of Action247 Sportsbook. Good luck!!

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* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.