UCLA vs Indiana Hoosiers NCAAF Betting Prediction
PublishedOctober 21, 2025,            Posted By: Maria Uebelhor
Last updated:October 21, 2025 ,

NCAAF UCLA Bruins vs Indiana Hoosiers Prediction 10/25

On Saturday, October 25, 2025, the UCLA Bruins will play against the Indiana Hoosiers at Memorial Stadium in Bloomington, IN. The game starts at 12:00 PM and will be shown on FOX. Indiana holds a perfect 7-0 record this season, while UCLA is 3-4.

UCLA vs. Indiana Betting Prediction

  • Money Line Prediction: UCLA Bruins +1379. UCLA has a strong record against the spread as an underdog, going 3-0 in their last 3 games. This makes them a good value pick for a potential upset.
  • Over/Under Prediction: Over 54.5. Indiana’s games have consistently gone over the total, especially at home, where they are 4-0 on the over this season.

Team Trends

  • Indiana Hoosiers have a perfect home record this season, standing at 5-0.
  • UCLA Bruins have a road record of 1-2 this season.
  • Indiana Hoosiers rank 3rd in points scored with 307 this season.
  • UCLA Bruins have a conference record of 3-1 in the Big Ten.
  • Indiana Hoosiers are ranked #2 in both the AP and Coaches Polls.

UCLA vs Indiana Preview

On Saturday, October 25, 2025, the UCLA Bruins will travel to Bloomington to play against the Indiana Hoosiers. The game will take place at Memorial Stadium and will be shown on FOX at 12:00 PM. UCLA has a 3-4 record this season, with a 3-1 record in conference play. They are currently on a three-game win streak, which gives them momentum going into this game.

The Indiana Hoosiers have been strong this season, holding a perfect 7-0 record. They are ranked #2 in both the AP and Coaches Polls. Indiana has been dominant at home with a 5-0 record. The Hoosiers will look to continue their seven-game win streak and maintain their top position in the Big Ten conference.

Indiana Hoosiers: Dominant Season Performance

Indiana Hoosiers hold the #2 rank in both the AP and Coaches Polls. They are undefeated with a 7-0 record this season. At home, they boast a 5-0 record, showing strength at Memorial Stadium.

The team has a solid offensive lineup with Fernando Mendoza leading as QB. He has thrown for 1,755 yards and 21 touchdowns this season. Roman Hemby and Kaelon Black contribute to the rushing game with over 400 yards each.

Defensively, Indiana has been strong, allowing only 81 points, ranking 38th in the nation. They have recorded 26 sacks and 10 interceptions, showing their defensive prowess. However, key players like Bryson Bonds and Tyler Morris are out for the season due to injuries.

UCLA Bruins: Road Challenges and Key Players

UCLA Bruins hold a 3-4 record this season, with a conference record of 3-1. On the road, they have won 1 out of 3 games. The Bruins recently defeated Maryland 20–17, showing they can compete.

Nico Iamaleava is the starting quarterback for UCLA, playing in all seven games. He has thrown for 1,355 yards and 10 touchdowns. On the ground, Jalen Berger leads with 232 rushing yards.

Defensively, UCLA has allowed 192 points, ranking 104th in the nation. The defense has recorded 6 sacks and 1 interception this season. Injuries could be a factor, with several players listed as questionable.

Final Betting Pick

The UCLA Bruins are a solid pick for the money line at +1379. They have a strong record against the spread as underdogs, going 3-0 in their last three games. This shows they can perform well when not favored, making them a good choice for an upset.

For the over/under, taking the over at 54.5 is a good option. Indiana’s games at home have consistently gone over, with a 4-0 record on the over this season. This trend suggests that high-scoring games are common for Indiana when they play at home.

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All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.