Virginia Cavaliers vs Duke Blue NCAAF Betting Prediction
PublishedNovember 11, 2025,            Posted By: Maria Uebelhor
Last updated:November 11, 2025 ,

NCAAF Virginia Cavaliers vs Duke Blue Prediction 11/15

The Virginia Cavaliers will take on the Duke Blue Devils on Saturday, November 15, 2025. This Week 12 game of the 2025 Regular Season will be held at Wallace Wade Stadium in Durham, NC. Tune in to ESPN2 at 3:30 PM to catch the action on the outdoor field.

Virginia vs. Duke Betting Prediction

  • Money Line Prediction: Virginia Cavaliers +190. Virginia has a strong road record this season, going 3-1. They are ranked #20 in the AP poll, which shows they are a competitive team.
  • Over/Under Prediction: Over 57.5. Both teams have shown the ability to score, with Duke’s offense ranked 22nd in points for and Virginia’s offense ranked 14th.

Team Trends

  • Virginia Cavaliers have an 8-2 record this season and are ranked #20 in the AP Poll.
  • Duke Blue Devils have a 5-4 record this season with a 2-2 record at home.
  • Virginia Cavaliers recently lost to Wake Forest Demon Deacons 16-9 at home.
  • Duke Blue Devils lost their last game to Connecticut Huskies 37-34.
  • The game will be played at Wallace Wade Stadium and will air on ESPN2.

Virginia vs Duke Preview

The Virginia Cavaliers come into this game with an 8-2 record. They are ranked #20 in the AP Poll and #19 in the Coaches Poll. The Cavaliers have performed well on the road this season, holding a 3-1 record. They are looking to bounce back from a recent loss and improve their 5-2 conference record. This game is important for them as they aim to climb higher in the Atlantic Coast standings.

On the other side, the Duke Blue Devils have a 5-4 record. They have been strong in conference play with a 4-1 record. At home, they have split their games, standing at 2-2. Duke is currently on a one-game losing streak and will aim to turn things around in front of their home crowd. This game is a chance for Duke to make a statement against a ranked opponent.

Inside the Duke Blue Devils’ Season So Far

The Duke Blue Devils are part of the Atlantic Coast Conference. They play their home games at Wallace Wade Stadium. This season, they have a record of 5-4, with a home record of 2-2.

Darian Mensah leads as the top quarterback with 2,794 passing yards in nine games. Nate Sheppard stands out as the top running back with 657 rushing yards and seven touchdowns. Cooper Barkate is the leading wide receiver with 824 receiving yards and five touchdowns.

Duke’s offense ranks 9th in passing yards with 2,816 yards. Their defense has allowed 262 points this season, ranking 113th. The team has recovered five fumbles, placing them 8th in that category.

Virginia Cavaliers Ready for Duke Challenge

The Virginia Cavaliers hold an impressive record of 8-2 this season. They rank #20 in the AP poll and #19 in the Coaches Poll. They have been strong on the road with a 3-1 record.

Chandler Morris leads the Cavaliers with 2,088 passing yards and 12 touchdowns. J’Mari Taylor is the top running back with 784 rushing yards and 11 touchdowns. Trell Harris leads the wide receivers with 605 receiving yards and four touchdowns.

Virginia’s offense has scored 337 points, ranking 14th in the nation. Their defense has allowed 216 points, ranking 94th. They have recovered five fumbles, placing them 8th in that category.

Final Betting Pick

Virginia Cavaliers have shown strong performance on the road this season with a 3-1 record. This makes the money line prediction of Virginia at +190 appealing. Their ranking at #20 in the AP poll indicates they are a competitive team. Virginia’s recent away games have been successful, which adds confidence to this pick.

The over/under prediction of over 57.5 is supported by both teams’ offensive capabilities. Duke’s offense is ranked 22nd in points for, while Virginia’s offense is ranked 14th. Both teams have shown they can score, making the over a reasonable choice. The trend of high-scoring games for both teams further supports this prediction.

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All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.