The Western Kentucky Hilltoppers will take on the LSU Tigers in Week 13 of the 2025 regular season. The game is set for Saturday, November 22, 2025, at 7:45 PM ET. It will be held at Tiger Stadium in Baton Rouge, LA, and will be broadcast on SECN.

Western Kentucky vs. LSU Betting Prediction

• Money Line Prediction: LSU Tigers -2142. LSU has a strong home record of 5-1 this season. Their overall performance at home makes them a solid choice.
• Over/Under Prediction: Over 50.5. Both teams have shown the ability to score, and the trends suggest a higher scoring game is likely.

Team Trends

• Western Kentucky has an 8-2 record this season with a 3-1 record on the road.
• LSU holds a 6-4 record this season and is 5-1 at home.
• Western Kentucky ranks 14th in passing yards with 2,961 yards this season.
• LSU’s defense has recorded 22 sacks, ranking 14th in the season.
• The game will be held at Tiger Stadium in Baton Rouge, LA, starting at 7:45 PM ET.

Western Kentucky vs LSU Preview

The Western Kentucky Hilltoppers are heading into Week 13 with an 8-2 record. They hold a strong conference record of 6-1 in Conference USA. The Hilltoppers are on a 3-game win streak and have been performing well on the road with a 3-1 record. They will face a challenge against the LSU Tigers at Tiger Stadium.

The LSU Tigers have a 6-4 record this season and have been solid at home with a 5-1 record. They are coming off a win and hold a conference record of 3-4 in the Southeastern Conference. Playing at Tiger Stadium gives LSU an advantage, as they aim to extend their win streak against the visiting Hilltoppers.

LSU Tigers: Home Performance and Season Overview

The LSU Tigers play in the Southeastern Conference and call Tiger Stadium in Louisiana home. This season, they hold a 6-4 record with an impressive 5-1 mark at home. In their last postseason game, they defeated the Baylor Bears 44-31 in the Kinder’s Texas Bowl.

The Tigers’ offense has been productive with 2,400 passing yards, ranking 61st. On the ground, they have accumulated 1,083 rushing yards, placing them 119th. Their defense is strong with 22 sacks and 12 interceptions, both of which are ranked 14th and 13th respectively.

Top players include QB Garrett Nussmeier with 1,925 passing yards and 12 touchdowns over nine games. RB Caden Durham has rushed for 447 yards and has 15 receptions. WR Zavion Thomas contributes with 396 receiving yards and 3 touchdowns in ten games.

Western Kentucky Hilltoppers: Road Warriors with Strong Offense

The Western Kentucky Hilltoppers are part of Conference USA. They play their home games at Houchens Industries–L.T. Smith Stadium. This season, they have an 8-2 record overall and a 3-1 record on the road.

Quarterback Maverick McIvor leads the passing attack with 1,863 yards and 12 touchdowns over seven games. Rodney Tisdale Jr. adds to the depth with 1,059 yards and nine touchdowns in five games. On the ground, Marvis Parrish has 427 rushing yards and 32 receptions, making him a key player.

The Hilltoppers’ defense has recorded 11 sacks and 7 interceptions, ranking them 24th and 8th respectively. They have scored 313 points this season, ranking 39th in the nation. In their last postseason game, they lost 27-17 to James Madison in the Boca Raton Bowl.

Final Betting Pick

LSU has been strong at home this season with a 5-1 record. Their recent win over Arkansas, 23-22, shows they can win close games. Playing at Tiger Stadium gives them an edge, making the money line prediction of LSU -2142 a solid choice.

The over/under prediction of over 50.5 is based on both teams’ scoring abilities. Western Kentucky scored 42 points in their last game against Middle Tennessee. LSU’s recent games have also seen high scores, like their 44-31 win over Baylor in the Texas Bowl. This trend suggests a higher-scoring game is likely.

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All odds are courtesy of Action247 Sportsbook. Good luck!!

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* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.