Arizona Cardinals vs Denver Broncos NFL Betting Prediction

NFL Arizona Cardinals vs Denver Broncos Prediction 8/16

The Arizona Cardinals will visit the Denver Broncos on Saturday, August 16, 2025, at 9:30 PM. This preseason Week 2 game will take place at Empower Field at Mile High in Denver, CO. The weather forecast predicts a very hot day with calm conditions and broken clouds. Fans can catch the action on NFLN. Both teams hold a 1-0 record in the preseason so far.

Cardinals vs. Broncos Betting Prediction

  • Money Line Prediction: Denver Broncos -252. The Broncos have a strong home record from last season, going 6-2. Their preseason performance also shows a solid defense, allowing only 9 points in their last game.
  • Over/Under Prediction: Under 40.5. Both teams have shown strong defensive performances in the preseason, with the Broncos allowing only 9 points and the Cardinals 17 points in their last games.

Team Trends

  • The Denver Broncos have a strong home record from last season, going 6-2-0 at Empower Field at Mile High.
  • Arizona Cardinals struggled on the road last season with a 2-6-0 record.
  • Both teams won their first preseason game this year, with the Cardinals defeating the Kansas City Chiefs and the Broncos beating the San Francisco 49ers.
  • Denver Broncos’ quarterback Jarrett Stidham threw for 136 yards and 2 touchdowns in their recent preseason win.
  • Arizona Cardinals’ defense had 2 interceptions in their preseason game against the Kansas City Chiefs.

Cardinals vs Broncos Preview

The Arizona Cardinals are set to play against the Denver Broncos in Week 2 of the preseason. Both teams won their first preseason games, making this an exciting matchup. The Cardinals finished the 2024 regular season with an 8-9 record, placing them third in the NFC West. The Broncos ended their regular season at 10-7, securing the third spot in the AFC West. This game will offer a chance for both teams to test their depth and strategies.

Jacoby Brissett will lead the Cardinals as the starting quarterback. He is projected to throw for 81 yards and two touchdowns. On the Broncos’ side, Jarrett Stidham is expected to start at quarterback, with projections of 136 passing yards and two touchdowns. Both teams will likely focus on evaluating their rosters, giving younger players a chance to shine under the lights at Empower Field at Mile High.

Denver Broncos Gearing Up

The Denver Broncos are looking strong with Sean Payton as head coach. In the 2024 season, they had a 10-7 regular season record, finishing third in their division. They played well at home with a 6-2 record.

Jarrett Stidham leads the quarterback lineup, with a projection of 136 passing yards and two touchdowns for this game. On the ground, Blake Watson is expected to rush for 28 yards. Wil Lutz, the kicker, adds to the team with three projected field goals.

The team offense scored an average of 30 points in the 2025 preseason, ranking 5th overall. Defensively, they allowed just nine points in the preseason, ranking 2nd. The Broncos aim to continue this momentum at Empower Field at Mile High.

Arizona Cardinals Ready to Compete

The Arizona Cardinals are under the guidance of head coach Jonathan Gannon. Last season, they had an 8-9 record and did not make the playoffs. This season, they have started the preseason with a win, aiming to improve on their road performance from last year.

Jacoby Brissett steps up as the starting quarterback, with a projection of 81 passing yards and two touchdowns. Kyler Murray, now in the backup role, is expected to add 96 passing yards. On the ground, Emari Demercado leads the running back lineup, projected to rush for seven yards with two receptions.

Wide receiver Xavier Weaver is anticipated to catch two passes for 14 yards and a touchdown. Kicker Chad Ryland adds strength to the team with two projected field goals. The Cardinals’ offense scored 20 points in the preseason, ranking 12th, while the defense allowed 17 points, ranking 5th.

Final Betting Pick

The Denver Broncos are a strong pick for the money line at -252. They have a solid home record of 6-2 from last season. Their recent preseason game showed a strong defense, allowing only 9 points against the 49ers. This defensive strength is a key factor in their favor.

The over/under prediction is set at under 40.5. Both teams have shown strong defensive performances in the preseason. The Broncos allowed only 9 points, while the Cardinals allowed 17 points in their last games. This trend suggests a low-scoring game, making the under a reasonable choice.


All odds are courtesy of Action247 Sportsbook. Good luck!!


* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.