The Kansas City Chiefs will play the Jacksonville Jaguars on Monday, October 6, 2025. This Week 5 game of the 2025 season will take place at EverBank Stadium in Jacksonville, FL. The game will start at 8:15 PM and will be broadcast on ABC.

Chiefs vs. Jaguars Betting Prediction

• Money Line Prediction: Kansas City Chiefs at -184. The Chiefs have a balanced road record of 1-1 this season. With Patrick Mahomes leading the offense, they have the edge over the Jaguars.
• Over/Under Prediction: Over 46.5. Both teams have shown the ability to score, with the Chiefs scoring 37 points in their last game and the Jaguars putting up 26 points against the 49ers.

Team Trends

• The Kansas City Chiefs have a balanced road record of 1-1-0 this season.
• The Jacksonville Jaguars have a perfect home record of 2-0-0 this season.
• Kansas City Chiefs’ head coach is Andy Reid, and their offensive coordinator is Matt Nagy.
• Jacksonville Jaguars’ head coach is Liam Coen, and their offensive coordinator is Grant Udinski.
• The game will be played at EverBank Stadium in Jacksonville, FL, and will air on ABC.

Chiefs vs Jaguars Preview

The Kansas City Chiefs are set to play against the Jacksonville Jaguars in Week 5 of the 2025 NFL season. The Chiefs come into this game with a 2-2 record, sitting second in the AFC West. Patrick Mahomes is projected to lead the team with 248.5 passing yards and 1.7 touchdowns. The Chiefs have won their last two games and will look to continue their streak.

The Jacksonville Jaguars have a 3-1 record, placing them second in the AFC South. Trevor Lawrence is expected to throw for 219.8 yards and 1.4 touchdowns. The Jaguars have won their last two games and aim to keep their momentum. Both teams will face off at EverBank Stadium, with the game starting at 8:15 PM on ABC.

Jaguars Gear Up for Game Day

Trevor Lawrence leads the Jacksonville Jaguars as quarterback. He is expected to throw for 219.8 yards with 1.4 touchdowns. Lawrence has zero interceptions projected for this game.

Running back Travis Etienne Jr. is key for the Jaguars. He is projected to rush for 63.3 yards and score 0.4 touchdowns. Etienne also contributes with 2.3 receptions.

Head coach Liam Coen guides the Jaguars this season. The team has a solid 3-1-0 record. They play at EverBank Stadium, where they are undefeated with a 2-0-0 home record.

Chiefs Ready for Action in Jacksonville

Patrick Mahomes leads the Kansas City Chiefs as quarterback. He is projected to throw for 248.5 yards with 1.7 touchdowns. Mahomes is expected to have no interceptions this game.

Running backs Isiah Pacheco and Kareem Hunt will be important for the Chiefs. Pacheco is expected to rush for 39.5 yards, while Hunt could add 32.1 yards. Both are projected to have around 1.8 receptions.

Andy Reid, the head coach, oversees the team. The Chiefs have a season record of 2-2-0, with a 1-1-0 record on the road. They aim to improve their AFC West division standing.

Final Betting Pick

The Kansas City Chiefs are a strong pick for the money line at -184. Patrick Mahomes is a key player, with a projected 248.5 passing yards and 1.7 touchdowns for this game. The Chiefs have shown they can win on the road, as seen in their victory against the New York Giants. Their balanced road record of 1-1 this season adds confidence to their ability to perform away from home.

The over 46.5 points is another solid choice. The Chiefs scored 37 points in their last game, while the Jaguars put up 26 points against the 49ers. Both teams have offenses capable of putting points on the board. With players like Travis Etienne Jr. and Trevor Lawrence on the Jaguars, and Mahomes leading the Chiefs, the game is likely to see a high score.

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All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.