The Kansas City Chiefs will play against the Tennessee Titans on Sunday, December 21, 2025. The game will take place at Nissan Stadium in Nashville, TN, and will be shown on CBS. The weather is expected to be cool with overcast clouds and a light breeze. The game starts at 1:00 PM.

Chiefs vs. Titans Betting Prediction

• Money Line Prediction: Kansas City Chiefs at -188. The Titans have struggled at home with a 0-7 record, while the Chiefs have a stronger overall performance despite their road challenges.
• Over/Under Prediction: Over 37.5. Both teams have shown the ability to score, and the Titans’ defense ranks low in opponent score, suggesting a higher total is possible.

Team Trends

• The Kansas City Chiefs have struggled on the road this season with a 1-5 record.
• The Tennessee Titans are still searching for their first home win this season with a 0-7 record.
• The Titans’ only win in the last five games came against the Cleveland Browns with a 31-29 score.
• Patrick Mahomes leads the Chiefs’ offense, but the team has lost their last five games.
• The game will be played at Nissan Stadium, where the weather is expected to be cool with overcast clouds.

Chiefs vs Titans Preview

The Kansas City Chiefs head to Nashville to play the Tennessee Titans in a Week 16 game. The Chiefs, with a 6-8 record, are third in the AFC West. They have struggled on the road this season, holding a 1-5 away record. Gardner Minshew leads the Chiefs’ offense, projected to throw for 249 yards and 1.5 touchdowns. Travis Kelce remains a key target, expected to add 48 yards and contribute to the passing game.

The Titans, sitting at the bottom of the AFC South with a 2-12 record, aim to break their losing streak. Cameron Ward, the Titans’ quarterback, is projected to pass for 190 yards and 1 touchdown. Tony Pollard is expected to lead the ground game with 56 rushing yards. The Titans will look to improve their home performance, having yet to win at Nissan Stadium this season.

Examining the Tennessee Titans

The Tennessee Titans have had a challenging season. With a record of 2-12, they have struggled to find consistency. Head Coach Mike McCoy is leading the team as they aim to improve their standing in the AFC South.

Quarterback Cameron Ward is the leading passer with 2,638 yards. He has thrown 11 touchdowns and 7 interceptions over 14 games. Running back Tony Pollard is another key player, having rushed for 847 yards and 5 touchdowns this season.

The Titans play at Nissan Stadium but have yet to secure a home win with a 0-7 home record. Injuries have been a significant issue, with several players on injured reserve. The defense ranks 27th in opponent scoring, allowing 460 points this season.

Unpacking the Kansas City Chiefs

The Kansas City Chiefs have a record of 6-8 this season. They are led by Head Coach Andy Reid. The Chiefs play their home games at Arrowhead Stadium. Gardner Minshew is set to start at quarterback. He is expected to throw for around 249 yards and 1-2 touchdowns. Running back Kareem Hunt is projected to rush for about 38 yards with a chance for a touchdown. Travis Kelce is a key player for the Chiefs. He ranks as a top tight end with 797 receiving yards and 5 touchdowns over 14 games. Harrison Butker is the team’s kicker, making 24 field goals this season.

Final Betting Pick

The Kansas City Chiefs are favored with a money line of -188. This is a good pick because the Chiefs have a better overall record than the Titans. Even though the Chiefs have struggled on the road, the Titans have not won at home this season.

The over/under is set at 37.5, and the over is a strong choice. Both teams have shown they can score, and the Titans’ defense ranks low in opponent score. With the Chiefs’ ability to pass effectively, the total points could easily exceed 37.5.

At Action 24/7, football game days come with more than just touchdowns — they come with bigger payouts. Every College Football Saturday and NFL Sunday, you’ll get a 10% College Football & NFL boost on spreads and totals. That means when your bets hit, you take home more. Simple, exciting, and only at Action 24/7.

---

All odds are courtesy of Action247 Sportsbook. Good luck!!

---

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.