The St. Louis Blues will take on the Buffalo Sabres on Thursday, November 6, 2025, at 7:00 PM. The game will be held at the KeyBank Center and will be broadcast on ESPN+. The Blues come into the game with a record of 4-8-2, while the Sabres hold a 5-5-4 record.

Blues vs. Sabres Betting Prediction

• Money Line Prediction: Buffalo Sabres MoneyLine: -137. The Sabres have a better record at home this season, and the Blues have struggled on the road, making Buffalo the safer choice.
• Over/Under Prediction: Under 6.5 (-119). Both teams have shown low-scoring games recently, with the Sabres’ last game ending 2-1 and the Blues scoring only once in their last outing.

Team Trends

• The Buffalo Sabres have a balanced record of 5-5-4 at the start of the season.
• St. Louis Blues hold a 4-8-2 record and are ranked 15th in their conference.
• In their last game, the Blues lost to the Washington Capitals with a score of 6-1.
• The Sabres recently lost a home game against the Utah Mammoth by a score of 2-1.
• Buffalo has one shutout win so far this season.

Blues vs Sabres Preview

The St. Louis Blues will travel to face the Buffalo Sabres at the KeyBank Center. The game is set for Thursday, November 6, 2025, at 7:00 PM. Fans can catch the action on ESPN+.

The Blues have a record of 4-8-2, while the Sabres stand at 5-5-4. Both teams are eager to improve their standings early in the NHL Regular Season.

Buffalo Sabres: Key Players and Stats

The Buffalo Sabres have some standout skaters this season. Alex Tuch leads the team with 12 points in 13 games. Tage Thompson and Rasmus Dahlin are also strong contributors with 10 and 9 points, respectively. Josh Doan has added depth to the Sabres’ offense with 9 points. Zach Benson, although not scoring goals, has provided 8 assists. Ryan McLeod has chipped in with 7 points, rounding out the forward lineup. In goal, Alex Lyon has played 10 games, earning 3 wins. He has made 301 saves but allowed 28 goals. Ukko-Pekka Luukkonen and Colten Ellis have each contributed with a win in their limited appearances.

St. Louis Blues: Players to Watch

The St. Louis Blues have a few players who are making a difference this season. Pius Suter leads the team with 9 points in 14 games. Jordan Kyrou and Jimmy Snuggerud are close behind with 8 points each. Jake Neighbours has scored 6 goals in just 8 games, adding energy to the lineup. Robert Thomas, with 8 points, is also a key player. Brayden Schenn has contributed with 6 points and adds physicality with 32 hits. In goal, Jordan Binnington has played 11 games and secured 3 wins. He has made 195 saves but allowed 32 goals. Joel Hofer has also played, earning 1 win with 112 saves.

Final Betting Pick

The Buffalo Sabres are a strong pick on the money line at -137. They have a solid home record this season, which gives them an edge. The St. Louis Blues have struggled on the road, with a record of 4-8-2, making it tough for them to secure wins away from home.

For the over/under prediction, going with under 6.5 at -119 seems wise. Both teams have had low-scoring games recently. The Sabres’ last game ended 2-1, and the Blues managed only one goal in their last outing. This trend suggests a lower-scoring game is likely.

All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.