The NBA regular season kicks off with an exciting game between the Cleveland Cavaliers and the New York Knicks. Both teams are starting fresh with a 0-0 record. The game will take place at Madison Square Garden on Wednesday, October 22, 2025, at 7:00 PM, and fans can catch it live on ESPN.

Cavaliers vs. Knicks Betting Prediction

• Spread Prediction: Knicks +1.5 (-111). The Knicks had a strong preseason with a 4-1 record, including 3-1 at home. This gives them an edge playing at Madison Square Garden.
• Over/Under Prediction: Under 228 (-110). Both teams are starting the regular season, and scoring might not be high as they adjust to regular season play.

Team Trends

• The NBA Regular Season is starting with the Cleveland Cavaliers playing against the New York Knicks.
• Both teams, Cavaliers and Knicks, have a current record of 0-0.
• The game will take place at Madison Square Garden.
• The game is scheduled for Wednesday, October 22, 2025, at 7:00 PM.
• Fans can watch the game on ESPN.

Cavaliers vs Knicks Preview

As the NBA regular season begins, the Cleveland Cavaliers and New York Knicks prepare to play at Madison Square Garden. The Cavaliers’ lineup features Lonzo Ball at point guard and Donovan Mitchell at shooting guard. Evan Mobley and Jarrett Allen will hold the frontcourt, aiming to control the paint against the Knicks.

The Knicks will counter with Jalen Brunson leading at point guard, supported by Jordan Clarkson. Mikal Bridges and OG Anunoby will add strength on the wings. Karl-Anthony Towns will play a key role in the post, looking to challenge Cleveland’s defense. Both teams aim for a strong start to the season, making this game one to watch.

New York Knicks Ready for Season Opener

The New York Knicks are set to start their season at Madison Square Garden. They will play against the Cleveland Cavaliers. The Knicks aim to make a strong impression in their first game. The Knicks have a good mix of players this season. They will rely on their home-court advantage. Fans will be eager to see how the team performs on opening night. The Knicks have been preparing for this game. Their goal is to improve their standing in the Eastern Conference. The game against the Cavaliers will be a chance to start the season on a high note.

Cleveland Cavaliers: Ready for a New Season

The Cleveland Cavaliers are starting their season with a fresh outlook. Kenny Atkinson, the head coach, leads the team. They are part of the Eastern Conference and play in the Central Division. During the preseason, the Cavaliers had a record of 1-3. They faced challenges on the road, going 0-2. However, they ended the preseason with a win, which can boost their confidence. The Cavaliers have some injury concerns. De’Andre Hunter is questionable with a knee issue. Darius Garland and Max Strus are out due to surgeries, which might affect their depth.

Final Betting Pick

The Knicks’ strong preseason record of 4-1, including a 3-1 performance at home, suggests they are ready to compete. Playing at Madison Square Garden gives them a familiar environment. This makes the Knicks +1.5 spread a reasonable choice.

Both teams are starting the regular season, so scoring might be lower as players adjust. The under 228 pick considers this adjustment period. With no regular season stats available yet, it’s hard to predict high scoring right away.

All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change.**All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk.Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.