On Thursday, November 27, 2025, the #22 Arkansas Razorbacks will take on the #4 Duke Blue Devils at 8:00 PM ET. The game will be held at the United Center in Chicago, IL, serving as a neutral site for this non-conference matchup. Fans can catch all the action on CBS as the Razorbacks, with a record of 5-1, face the undefeated Blue Devils, who stand at 7-0 this season.

Arkansas vs. Duke Betting Prediction

• Spread Prediction: Duke -10.5 (-107). Duke has a strong record both straight up and against the spread. They are 7-0 overall and 5-1 ATS, making them a solid pick to cover the spread.
• Over/Under Prediction: Under 156.5 (-111). Both teams have been trending towards the under. Duke’s games have gone under in 6 of their 7 games, and Arkansas has hit the under in 4 of their 6 games.

Team Trends

• The game will be played at the United Center in Chicago, a neutral site for both teams.
• Duke Blue Devils are the favorite with a spread of -10.5, while Arkansas Razorbacks have a spread of +10.5.
• Arkansas Razorbacks have a MoneyLine of +410, indicating they are the underdog.
• Duke Blue Devils have not lost a game in their last 10 straight-up contests, holding a 7-0 record.
• Arkansas Razorbacks have a straight-up record of 5-1 in all games but have struggled as underdogs with a 0-1 record.

Arkansas vs Duke Preview

The Arkansas Razorbacks, ranked #22, are set to play against the #4 Duke Blue Devils on Thursday, November 27, 2025. The game will be held at the United Center in Chicago, a neutral site for both teams. Arkansas enters the game with a 5-1 record, having won their last game against Jackson State with a score of 115-61.

Duke holds a perfect 7-0 record this season. In their recent game, they defeated Howard with a score of 93-56. The Blue Devils have been strong both at home and away, making them the favorite in this matchup. Fans can watch this exciting game on CBS at 8:00 PM ET.

Duke Blue Devils Dominate on the Court

The Duke Blue Devils are ranked #4 in the nation. They have a strong start to the season with a perfect 7-0 record. Their success is evident both at home and away, with 4 wins at home and 3 on the road. In recent games, Duke showed impressive performances. They defeated Howard Bison 93-56 and Niagara Purple Eagles 100-42. Cameron Boozer stood out with 26 points against Howard and 18 points against Kansas. Duke’s offense is strong, averaging 93.6 points per game. They have a high field goal percentage of 52.4%. Their defense also plays a key role, allowing only 66 points against Kansas.

Arkansas Razorbacks Seek to Challenge Duke

The Arkansas Razorbacks have a strong start this season. They hold a 5-1 record, with all wins at home. Their only loss came on the road, making this upcoming game a test for their away performance. Arkansas averages 91 points per game, ranking 34th in the nation. Their field goal percentage is 49.9%, showing efficient scoring. They also excel at free throws, with a 79.9% success rate, ranking 7th. Key players include Meleek Thomas and Darius Acuff Jr. Thomas averages 18.3 points per game, while Acuff Jr. adds 16.8 points per game. Their contributions will be vital against Duke’s strong defense.

Final Betting Pick

Duke is favored by 10.5 points, and this seems like a strong choice. Duke has a perfect 7-0 record and has covered the spread in 5 of 6 games. With their high-scoring offense, averaging 93.6 points per game, they have the firepower to win by a large margin.

The over/under is set at 156.5, and taking the under is a smart move. Duke’s games have gone under in 6 of their 7 games. Arkansas has also seen the under hit in 4 of their 6 games, making this trend likely to continue.

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All odds are courtesy of Action247 Sportsbook. Good luck!!

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* All odds are provided by Action247 Sportsbook and all odds subject to change.**All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk.Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.