On Tuesday, December 9, 2025, the Clemson Tigers will take on the #10 BYU Cougars at Madison Square Garden in New York, NY. This non-conference game will be a neutral site event, starting at 6:30 PM ET and airing on ESPN. The BYU Cougars, ranked 10th and playing in the Big 12, are favored with a spread of -7.5, while the Clemson Tigers, from the Atlantic Coast Conference, are the underdogs with a spread of +7.5.

Clemson vs. BYU Betting Prediction

• Spread Prediction: Clemson +7.5. Clemson has a strong ATS trend, going 3-0 in their last three games. This makes them a good value with the points.
• Over/Under Prediction: Over 150.5. Clemson has hit the over in their last three games, and both teams score over 85 points per game.

Team Trends

• The Clemson Tigers are the underdog with a spread of +7.5 against the BYU Cougars.
• BYU Cougars have a strong SU record as a favorite, winning all 7 games.
• Clemson Tigers have been successful ATS as an underdog, with a 1-0 record.
• The game will be held at Madison Square Garden, a neutral site.
• BYU Cougars are favored to win with a moneyline of -335.

Clemson vs BYU Preview

The Clemson Tigers and the #10 BYU Cougars will meet at Madison Square Garden on December 9, 2025. Clemson comes into this game with a record of 7-2, showing strength at home but an even split on the road. Their recent loss to Alabama was close, ending 90-84, but they had strong performances from RJ Godfrey and Dillon Hunter. Clemson will look to bounce back against a tough opponent.

BYU, ranked 10th, holds a 7-1 record and has been solid both at home and away. They recently defeated California Baptist by 31 points, with standout performances from Keba Keita and Robert O. Wright III. As the favorite with a -7.5 spread, BYU will aim to continue their winning streak. This game will be broadcast on ESPN at 6:30 PM ET.

BYU Cougars: A Strong Start to the Season

The BYU Cougars have started the 2026 season with a 7-1 record. They have been strong at home, winning 5 out of 6 games. On the road, they have been perfect, winning both games they played. In their most recent game, the Cougars defeated California Baptist Lancers by 31 points. Keba Keita and AJ Dybantsa both scored 22 points in that game. Robert O. Wright III added 15 points and had 11 assists. The Cougars are ranked #10 and play in the Big 12 Conference. They score an average of 85.2 points per game. Their field goal percentage is 49.4%, which ranks them 48th in the nation.

Clemson Tigers: Ready for the Challenge

The Clemson Tigers have a record of 7-2 this season. They have been strong at home, winning all five games. On the road, they have been less consistent, with a 2-2 record. In their last game, the Tigers lost to Alabama Crimson Tide by 6 points, with a score of 90-84. RJ Godfrey led the team with 19 points, while Dillon Hunter added 13 points. Their field goal percentage was 40.8% in that game. Clemson scores an average of 85.1 points per game, ranking 68th in the nation. They have a field goal percentage of 46.2%. RJ Godfrey is a key player, averaging 12.1 points and 6.4 rebounds per game.

Final Betting Pick

Clemson is a solid pick with a +7.5 spread. They have a good record against the spread, going 3-0 in their last three games. With their strong performance, they can keep the game close against BYU.

The over 150.5 is also a smart choice. Both Clemson and BYU score over 85 points per game. Their offensive stats suggest a high-scoring game, which supports the over prediction.

All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change.**All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk.Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.