Iowa State Cyclones vs Purdue Boilermakers NCAAB Betting Prediction

NCAAB Iowa State Cyclones vs Purdue Prediction 12/6

On Saturday, December 6, 2025, the #10 Iowa State Cyclones will play against the #1 Purdue Boilermakers at Mackey Arena in West Lafayette, IN. This non-conference game will be broadcast on CBS at 12:00 PM ET. Both teams have perfect 8-0 records this season, with Purdue favored by 5.5 points. The over/under for the game is set at 153.5 points.

Iowa State vs. Purdue Betting Prediction

  • Spread Prediction: Iowa State +5.5. Iowa State has a strong record against the spread, covering in 75% of their games. They have also been perfect straight up this season.
  • Over/Under Prediction: Over 153.5. Iowa State scores a lot of points per game, and their games have hit the over 75% of the time this season.

Team Trends

  • The game will be held at Mackey Arena in West Lafayette, Indiana.
  • Iowa State Cyclones have a perfect 8-0 record in all games this season.
  • Purdue Boilermakers are favored with a spread of -5.5.
  • Iowa State has a strong Over/Under trend with 6-2 in their last 10 games.
  • The game will be broadcast on CBS.

Iowa State vs Purdue Preview

On Saturday, December 6, 2025, the Iowa State Cyclones will visit the Purdue Boilermakers at Mackey Arena. Both teams are off to strong starts with 8-0 records. This game will be shown on CBS at noon ET.

Iowa State recently beat Alcorn State with a score of 132-68. Purdue also had a big win, defeating Eastern Illinois 109-62. The Boilermakers are favored by 5.5 points. The over/under is set at 153.5 points, indicating a high-scoring game might be in store.

Purdue Boilermakers: Dominating the Court

The Purdue Boilermakers are off to a strong start this season. They hold the top spot in the AP rankings and have an unblemished record of 8-0. At Mackey Arena, they have been unbeatable with a 5-0 home record. In their recent game against Rutgers, Purdue secured a win by 16 points. Trey Kaufman-Renn stood out with 19 points and 13 rebounds. This performance helped Purdue maintain their perfect record. Purdue’s offense is one of the best in the country, scoring 88.6 points per game. Their field goal percentage is 51.0%, ranking them 25th nationally. With a 3-point percentage of 41.8%, they are a threat from beyond the arc.

Iowa State Cyclones: Aiming High

The Iowa State Cyclones are having a great season so far. They are ranked 10th in the AP rankings with an 8-0 record. Their recent victory over Alcorn State was by a huge margin of 64 points. Iowa State’s offense is strong, averaging 96.2 points per game, which ranks 4th in the nation. Their field goal percentage is the best in the country at 55.0%. From beyond the arc, they shoot 43.3%, placing them 3rd nationally. Key players like Joshua Jefferson and Milan Momcilovic are making an impact. Jefferson averages 18.4 points and 7.2 rebounds per game. Momcilovic contributes with 18.1 points per game and a 54.8% 3-point shooting percentage.

Final Betting Pick

Choosing Iowa State with a +5.5 spread looks promising. Iowa State has covered the spread in 75% of their games. Their perfect straight-up record shows they can compete with top teams.

The over 153.5 points is also a solid pick. Iowa State scores 96.2 points per game, ranking them 4th. Their games often hit the over, making this a likely outcome against Purdue.


All odds are courtesy of Action247 Sportsbook. Good luck!!


* All odds are provided by Action247 Sportsbook and all odds subject to change.**All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk.Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.