The Clemson Tigers will play against the South Carolina Gamecocks on Saturday, November 29, 2025. This game is part of Week 14 of the regular season. It will take place at Williams-Brice Stadium in Columbia, SC, and is set to start at 12:00 PM. You can watch the game on SECN.

Clemson vs. South Carolina Betting Prediction

• Money Line Prediction: Clemson Tigers +117. Clemson has a strong road record this season at 3-1. They have also been successful in away games over the past two years.
• Over/Under Prediction: Under 46.5. Both teams have shown defensive strength, and their recent games have not consistently exceeded this total.

Team Trends

• Clemson Tigers have a 3-1 road record this season.
• South Carolina Gamecocks have a 3-3 home record this season.
• Clemson Tigers’ offense ranks 23rd in passing yards with 3,020 yards this season.
• South Carolina Gamecocks’ defense ranks 4th in fumbles recovered with 10 this season.
• South Carolina Gamecocks won their last home game against Coastal Carolina 51-7.

Clemson vs South Carolina Preview

The Clemson Tigers are heading into this game with a 6-5 record. They have been strong on the road, winning 3 out of 4 games. Clemson is on a 3-game win streak, which gives them confidence. They are looking to improve their conference record of 4-4 as they face South Carolina.

On the other side, the South Carolina Gamecocks hold a 4-7 record. They have a balanced home record of 3-3 but have struggled in conference games with a 1-7 record. The Gamecocks are coming off a win, which they hope to build on against Clemson. Playing at home, South Carolina aims to end their season on a positive note.

South Carolina Gamecocks Overview

The South Carolina Gamecocks play in the Southeastern Conference. They play their home games at Williams-Brice Stadium. Their current season record stands at 4-7.

Quarterback LaNorris Sellers has played in 11 games this season. He has thrown for 2,056 passing yards, 11 touchdowns, and 6 interceptions. Sellers ranks first on the team in these categories.

Running back Rahsul Faison leads the team in rushing with 433 yards and 3 touchdowns. Wide receiver Nyck Harbor has 503 receiving yards and 5 touchdowns in 10 games. Kicker William Joyce has made 12 field goals and 29 extra points this season.

Clemson Tigers Ready for Road Challenge

The Clemson Tigers compete in the Atlantic Coast Conference. Their current season record is 6-5. Clemson plays home games at Memorial Stadium in Clemson, South Carolina.

Quarterback Cade Klubnik has thrown for 2,482 yards, 16 touchdowns, and 5 interceptions in 10 games. He leads the team in passing statistics. Running back Adam Randall has rushed for 677 yards and scored 8 touchdowns over 11 games.

Wide receiver T.J. Moore has 653 receiving yards and 4 touchdowns in 11 games. Kicker Nolan Hauser made 14 field goals and 35 extra points this season. Clemson’s defense ranks 11th in sacks and 8th in interceptions and fumbles recovered.

Final Betting Pick

Clemson’s money line at +117 is a solid pick. They have an impressive 3-1 record on the road this season. Over the past two years, they have shown strength in away games, winning 8 out of their last 9. This makes them a strong contender against South Carolina, who has struggled with a 1-7 conference record.

The under 46.5 prediction is based on both teams’ defensive abilities. Clemson’s defense ranks 11th in sacks and 8th in interceptions, while South Carolina also ranks well in interceptions and fumbles recovered. Recent games for both teams have not often gone over this total, indicating a likelihood of a lower-scoring game.

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All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.