The Duke Blue Devils will visit the North Carolina Tar Heels on Saturday, November 22, 2025. This Week 13 game will take place at Kenan Stadium in Chapel Hill, NC. Kickoff is set for 3:30 PM, and fans can catch the action on ACCN.

Duke vs. North Carolina Betting Prediction

• Money Line Prediction: Duke Blue Devils at -255. Duke has a better record on the road this season with 3 wins and 2 losses. North Carolina has struggled at home with a 2-3 record.
• Over/Under Prediction: Over 51.5. Duke’s last three away games have all gone over the total, making the over a good choice.

Team Trends

• Duke has a 3-2 record on the road this season.
• North Carolina has a 2-3 record at home this season.
• Duke ranks 11th in passing yards with 3,029 this season.
• North Carolina ranks 8th in sacks with 28 this season.
• Duke’s last postseason game was a loss to Ole Miss, 52-20, in the TaxSlayer Gator Bowl.

Duke vs North Carolina Preview

The Duke Blue Devils and North Carolina Tar Heels are set for an exciting game at Kenan Stadium. Duke comes in with a 5-5 record, looking to improve their standing in the Atlantic Coast Conference. Their road performance has been solid, with a 3-2 record. However, they are on a two-game losing streak, which they hope to break against their rivals.

North Carolina, with a 4-6 record, aims to defend their home turf. Their conference record stands at 2-4, and they are ranked 12th in the conference. The Tar Heels are coming off a loss and will be eager to turn things around. Both teams are unranked, but this game holds significance as they vie for a better conference position.

North Carolina Tar Heels: Season Overview

The North Carolina Tar Heels are part of the Atlantic Coast Conference. They play their home games at Kenan Stadium. Their current season record stands at 4-6, with a home record of 2-3.

Gio Lopez leads the team as quarterback, playing in nine games this season. He has passed for 1,425 yards, eight touchdowns, and five interceptions. In the running back position, Demon June has rushed for 452 yards and scored two touchdowns over nine games.

On the defensive side, the Tar Heels have allowed 220 points and have made 28 sacks. They have also intercepted six passes and recovered six fumbles. These efforts place them at 80th in points against and 8th in sacks nationally.

Duke Blue Devils: Road Warriors in Action

Duke Blue Devils have a record of 5-5 this season. Their road record stands at 3-2, showing they play well away from home. In the Atlantic Coast Conference, they hold a 4-2 record.

Darian Mensah is the Blue Devils’ quarterback. He has racked up 3,007 passing yards with 25 touchdowns over 10 games. Nate Sheppard, a key running back, has rushed for 700 yards and scored seven touchdowns.

Defensively, Duke has allowed 296 points and ranks 16th with 20 sacks. They have managed 10 interceptions and five fumble recoveries. Their defense shows strength, despite allowing a high number of points.

Final Betting Pick

Duke is a strong pick on the money line at -255. They have shown good performance on the road with a 3-2 record. This is better than North Carolina’s home record of 2-3. Duke has a history of winning as favorites, with a 22-5 record in their last 27 games.

The over 51.5 is a solid choice for this game. Duke’s last three away games have all gone over the total. Their offense ranks 11th in passing yards, which can lead to high-scoring games. North Carolina’s defense ranks 80th in points against, which might allow Duke to score more.

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All odds are courtesy of Action247 Sportsbook. Good luck!!

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* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.