The Iowa State Cyclones will take on the Colorado Buffaloes in Week 7 of the 2025 regular season. The game is set for Saturday, October 11, 2025, at 3:30 PM at Folsom Field in Boulder, CO. Fans can catch the action on ESPN.

Iowa State vs. Colorado Betting Prediction

• Money Line Prediction: Iowa State at -160. Iowa State has a strong record this season with 5 wins and 1 loss. They have also been successful in away games, winning 9 of their last 12.
• Over/Under Prediction: Over 52.5. Both teams have shown the ability to score, with Iowa State scoring 188 points this season and Colorado scoring 150. This suggests the total could go over.

Team Trends

• Iowa State Cyclones are ranked #22 in the AP Poll and #21 in the Coaches Poll.
• Colorado Buffaloes have a home record of 2-2 this season.
• Iowa State Cyclones have a road record of 1-1 this season.
• Colorado Buffaloes lost their last home game against BYU Cougars, 24-21.
• Iowa State Cyclones’ last away game was a loss to Cincinnati Bearcats, 38-30.

Iowa State vs Colorado Preview

The Iowa State Cyclones are heading into this game with a strong 5-1 record. Ranked #22 in the AP poll, they have shown solid performance this season. Their only loss came on the road, which they aim to improve against the Colorado Buffaloes. The Cyclones have a conference record of 2-1, putting them in a good position in the Big 12 standings.

The Colorado Buffaloes have had a tougher season with a 2-4 record. They are looking to break a two-game losing streak. Playing at home, the Buffaloes hope to use Folsom Field to their advantage. Despite their struggles, they will aim to secure their first conference win of the season against a ranked opponent.

Colorado Buffaloes: Team Overview and Stats

The Colorado Buffaloes play in the Big 12 Conference. Their home games are at Folsom Field. This season, they have a record of 2-4, with a 2-2 record at home.

Quarterback Kaidon Salter has played in five games. He has thrown for 901 yards, seven touchdowns, and four interceptions. Ryan Staub has contributed in two games with 361 yards, three touchdowns, and two interceptions.

Running back Micah Welch leads the team with 250 rushing yards and one touchdown in six games. Wide receiver Omarion Miller has made 17 catches for 289 yards and three touchdowns. The team has scored 150 points and allowed 149 points this season.

Iowa State Cyclones: A Strong Start to the Season

The Iowa State Cyclones have had a good season so far. They hold a 5-1 record, with a 1-1 record on the road. They are ranked #22 in the AP Poll and #21 in the Coaches Poll, showing strong performances this year.

Rocco Becht leads the Cyclones as quarterback. He has thrown for 1,417 yards and nine touchdowns in six games. Carson Hansen is the top running back with 348 rushing yards and two touchdowns in six games.

Iowa State’s defense has been strong, allowing 109 points this season. They have nine sacks and six interceptions, making it hard for opponents to score. The Cyclones are favorites in their upcoming game, aiming to continue their winning ways.

Final Betting Pick

Iowa State looks solid with a money line of -160. They have a strong record of 5-1 this season. Their performance in away games is impressive, with 9 wins in their last 12 road games. This shows they can handle the pressure of playing away from home.

The over/under prediction is set at 52.5. Iowa State has scored 188 points this season, while Colorado has scored 150. Both teams have shown they can put points on the board. This makes the over a good choice, as both teams are likely to score enough to surpass the total.

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All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.