Iowa State Cyclones vs Kansas Jayhawks NCAAB Betting Prediction
PublishedNovember 18, 2025,            Posted By: Maria Uebelhor
Last updated:November 18, 2025 ,

NCAAF Kansas Jayhawks vs Iowa State Prediction 11/22

The Kansas Jayhawks will take on the Iowa State Cyclones in Week 13 of the 2025 season. This game is set for Saturday, November 22, 2025, at Jack Trice Stadium in Ames, IA. Fans can catch the action at 12:00 PM on FS1. The Cyclones have a 6-4 record, while the Jayhawks stand at 5-5 this season. Both teams are part of the Big 12 Conference.

Kansas vs. Iowa State Betting Prediction

  • Money Line Prediction: Iowa State Cyclones -189. Iowa State has a strong home record of 4-2 this season. They have been solid at home, making them a good pick to win.
  • Over/Under Prediction: Over 55.5. Kansas games have gone over in 19 out of their last 30 away games. This trend suggests a higher-scoring game is likely.

Team Trends

  • The Kansas Jayhawks have a road record of 1-3 this season.
  • Iowa State Cyclones hold a home record of 4-2 this season.
  • Kansas Jayhawks rank 5th in interceptions with 4 this season.
  • Iowa State Cyclones have scored 271 points this season, ranking 56th.
  • The game will be played at Jack Trice Stadium in Ames, IA.

Kansas vs Iowa State Preview

The Kansas Jayhawks are set to play against the Iowa State Cyclones in Week 13 of the 2025 season. The game will take place at Jack Trice Stadium in Ames, IA, on November 22, 2025. Fans can tune in at 12:00 PM on FS1. The Jayhawks have a 5-5 record, while the Cyclones hold a 6-4 record. Both teams are in the Big 12 Conference.

Kansas has struggled on the road with a 1-3 record, but they aim to improve. Iowa State has been strong at home, winning 4 out of 6 games. The Cyclones come into this game with a one-game win streak. The Jayhawks are looking to end their current one-game losing streak. Both teams have a conference record of 3-4, making this game important for their standings.

Iowa State Cyclones: Team Overview

Iowa State Cyclones play in the Big 12 Conference and host games at Jack Trice Stadium. They have a 6-4 record this season, with a 4-2 record at home. In their last postseason game, the Cyclones won against the Miami Hurricanes, 42-41, at the Pop-Tarts Bowl.

Rocco Becht is the leading quarterback for Iowa State. He has played in 10 games with 2,230 passing yards and 12 touchdowns. On the ground, Carson Hansen leads the rushing attack with 721 yards and 5 touchdowns over 9 games.

The team’s offense has scored 271 points this season, ranking 56th in the country. They have passed for 2,303 yards and rushed for 1,643 yards. On defense, they have allowed 215 points, ranking 77th, with 11 sacks and 9 interceptions.

Kansas Jayhawks: Season Snapshot

The Kansas Jayhawks play in the Big 12 Conference and call David Booth Kansas Memorial Stadium their home. This season, they hold a 5-5 record, with a 1-3 record on the road. In their last game, they lost to Arizona 24-20.

Jalon Daniels is the standout quarterback for the Jayhawks. He has thrown for 2,190 yards with 21 touchdowns in 10 games. On the ground, Leshon Williams leads with 419 rushing yards and 6 touchdowns, while Daniel Hishaw Jr. has added 430 rushing yards and 4 touchdowns.

The Jayhawks’ offense has scored 302 points, ranking 44th in the country. They have passed for 2,289 yards and rushed for 1,629 yards. On defense, they have allowed 252 points, which ranks them 97th, and they have recorded 24 sacks and 4 interceptions.

Final Betting Pick

Iowa State’s strong home record makes them a solid pick for the money line at -189. They have won 10 of their last 13 home games, showing they perform well at Jack Trice Stadium. Their recent win against TCU adds confidence to their ability to secure another victory.

The over 55.5 prediction is supported by Kansas’ trend of high-scoring away games. In their last 30 away games, 19 have gone over. This suggests that when Kansas plays away, games often see more points, making the over a reasonable choice for this matchup.

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All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.