In Week 14 of the 2025 regular season, the Kentucky Wildcats will play against the Louisville Cardinals. The game is set for Saturday, November 29, 2025, at 12:00 PM. It will take place at L&N Federal Credit Union Stadium in Louisville, KY, and will be broadcast on ACCN.

Kentucky vs. Louisville Betting Prediction

• Money Line Prediction: Louisville Cardinals -153. Louisville has a better season record and a strong home record. Kentucky has struggled on the road with a 1-3 record.
• Over/Under Prediction: Over 47.5. Both teams have shown they can score, and Kentucky’s recent games have often gone over the total.

Team Trends

• Kentucky Wildcats have a road record of 1-3 this season.
• Louisville Cardinals have a home record of 4-3 this season.
• Kentucky’s defense ranks 15th in sacks with 24 this season.
• Louisville’s offense has scored 321 points, ranking 49th this season.
• In their last game, Louisville lost to SMU Mustangs 38-6.

Kentucky vs Louisville Preview

The Kentucky Wildcats and Louisville Cardinals are set for a game in Week 14 of the 2025 season. Kentucky has a record of 5-6, with struggles on the road at 1-3. They play in the Southeastern Conference and are coming off a one-game loss streak. Louisville, with a 7-4 record, has been stronger at home, holding a 4-3 record at L&N Federal Credit Union Stadium.

Louisville is in the Atlantic Coast Conference and is currently on a three-game losing streak. Both teams are unranked in the AP and Coaches polls. The Wildcats are ranked 11th in their conference, while the Cardinals are 8th. This game offers a chance for both teams to end the regular season on a positive note.

Louisville Cardinals: Season Overview

The Louisville Cardinals play in the Atlantic Coast Conference. Their home games are held at L&N Federal Credit Union Stadium. This season, their record stands at 7-4 with a home record of 4-3.

The Cardinals’ offense scored 321 points this season, ranking them 49th. They accumulated 2,533 passing yards, placing them at 66th in the rankings. Their rushing yards total 1,703, ranking them 72nd.

Defensively, Louisville allowed 253 points, ranking 91st. They recorded 21 sacks, which is 18th in the rankings. The team also achieved 12 interceptions, placing them 13th overall.

Kentucky Wildcats: Season Insights

The Kentucky Wildcats play in the Southeastern Conference. They play their home games at Kroger Field. This season, their record is 5-6, with a road record of 1-3.

On offense, the Wildcats scored 276 points, which ranks 70th. Their passing yards for the season are 2,323, placing them at 83rd. Kentucky’s rushing yards total 1,637, ranking them 77th.

Defensively, Kentucky allowed 276 points, ranking 104th. They recorded 24 sacks, which is 15th in the rankings. The Wildcats also secured 12 interceptions, placing them 13th overall.

Final Betting Pick

The Louisville Cardinals are a solid pick for the money line at -153. They have a better overall record this season at 7-4. Louisville has also been strong at home with a 4-3 record. Kentucky, on the other hand, has struggled on the road with a 1-3 record. Louisville’s recent performance at home gives them an edge in this game.

For the over/under, the prediction is over 47.5. Both teams have shown they can score points. Kentucky’s recent games have often gone over the total. Louisville’s offense ranks 49th in points for, which suggests they can contribute to a high-scoring game. These factors make the over a favorable choice for this matchup.

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All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.