The Michigan Wolverines will play against the USC Trojans on Saturday, October 11, 2025. This game is part of Week 7 of the regular season. It will take place at the Los Angeles Memorial Coliseum in Los Angeles, CA, and will be broadcast on NBC at 7:30 PM.

Michigan vs. USC Betting Prediction

• Money Line Prediction: Michigan Wolverines +116. Michigan has a strong record when playing away, with a 78.3% success rate in their last 23 games. Their recent win over Wisconsin also shows they are in good form.
• Over/Under Prediction: Over 57.5. USC games at home often go over, with a 76.7% rate in their last 30 home games. Both teams have strong offenses, which could lead to a high-scoring game.

Team Trends

• The Michigan Wolverines have a road record of 1-1 this season.
• The USC Trojans are undefeated at home this season with a 3-0 record.
• Michigan ranks 8th in both sacks and interceptions this season.
• USC has scored 242 points this season, ranking 5th in the nation.
• The game will be played at the Los Angeles Memorial Coliseum and aired on NBC.

Michigan vs USC Preview

The Michigan Wolverines head into Week 7 with a 4-1 record. They are ranked 15th in both the AP and Coaches Polls. The Wolverines have a strong conference record of 2-0 and are on a three-game win streak. Their only loss came on the road, so they will aim to improve their road performance in this game.

The USC Trojans also hold a 4-1 record. They have a 2-1 conference record and are undefeated at home this season. However, they are coming off a loss and will look to bounce back at the Los Angeles Memorial Coliseum. Both teams are part of the Big Ten conference, adding more excitement to this game.

USC Trojans: Team Overview and Performance

The USC Trojans play in the Big Ten Conference and host their games at the Los Angeles Memorial Coliseum. This season, they have a record of 4-1, with a strong 3-0 record at home. They are coming off a narrow 32-34 loss to Illinois, but they have a history of bouncing back after losses with a 3-0 record in such situations.

Jayden Maiava leads the Trojans as quarterback with 1,587 passing yards, ranking first on the team. Running back Waymond Jordan has contributed with 537 rushing yards and 5 touchdowns. Makai Lemon is a standout wide receiver, boasting 589 receiving yards and 5 touchdowns, placing him first on the team in both categories.

The Trojans have scored 242 points this season, ranking 5th in their conference. Their passing game has gained 1,690 yards, ranking 8th, while their defense has allowed 115 points. The defense also excels in sacks, with 17 this season, placing them 7th in the league.

Michigan Wolverines: A Look at the Season and Key Players

The Michigan Wolverines hold a 4-1 record this season. They are ranked #15 in both the AP and Coaches Polls. They are coming off a strong 24-10 win over Wisconsin and have a solid conference record of 2-0.

Bryce Underwood is the top quarterback for Michigan. He has thrown for 1,003 yards and 3 touchdowns in five games. Running back Justice Haynes is another key player, rushing for 654 yards and 8 touchdowns.

On the receiving end, Donaven McCulley leads the team with 19 receptions and 309 yards. The Wolverines’ defense is strong, with 16 sacks and 7 interceptions, ranking them 8th in both categories. They are facing some injuries, including Jaydon Hood and I’Marion Stewart, who will miss the rest of the season.

Final Betting Pick

Michigan has shown strength in away games with a 78.3% win rate in their last 23 games. This includes a recent win over Nebraska, where they scored 30 points. Their ability to perform well on the road makes the money line prediction of Michigan Wolverines +116 a solid choice.

The over/under prediction of over 57.5 is supported by USC’s home game trends. USC games at home often go over, with a 76.7% rate in their last 30 home games. Both teams have strong offenses, with Michigan’s rushing attack and USC’s passing game, suggesting a high-scoring game is likely.

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All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.